Mechanisms underlying extensive Ser129-phosphorylation in α-synuclein aggregates
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-017-0452-6
Abstract: Parkinson’s disease (PD) is characterized neuropathologically by intracellular aggregates of fibrillar α-synuclein, termed Lewy bodies (LBs). Approximately 90% of α-synuclein deposited as LBs is phosphorylated at Ser129 in brains with PD. In contrast, only 4%… read more here.
Keywords: total synuclein; phosphorylation; ser129 phosphorylation; synuclein ... See more keywords