Verapamil Inhibits Ser202/Thr205 Phosphorylation of Tau by Blocking TXNIP/ROS/p38 MAPK Pathway
Sign Up to like & getrecommendations! Published in 2017 at "Pharmaceutical Research"
DOI: 10.1007/s11095-017-2276-2
Abstract: PurposeOxidative stress is a hallmark of Alzheimer’s Disease (AD) and promotes tau phosphorylation. Since Thioredoxin Interacting protein (TXNIP), the inhibitor of the anti-oxidant system of Thioredoxin, is up regulated in the hippocampus of AD patients,… read more here.
Keywords: p38 mapk; ser202 thr205; verapamil; tau phosphorylation ... See more keywords