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   Articles with "seraph 100" as a keyword



Seraph 100 Microbind Affinity Blood Filter for Persistent Pediatric BK Virus Nephropathy

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recommendations! Published in 2025 at "Pediatric Transplantation"

DOI: 10.1111/petr.70055

Abstract: Resolution of BK viremia is almost universally required before kidney transplant. Unfortunately, proven anti‐BK viral therapies are limited. The Seraph 100 mimics the action of the natural glycocalyx, which binds pathogens via heparin sulfate proteoglycans.… read more here.

Keywords: filter; seraph 100; microbind affinity; 100 microbind ... See more keywords

Hemoperfusion with Seraph 100 Microbind Affinity Blood Filter Unlikely to Require Increased Antibiotic Dosing: A Simulations Study Using a Pharmacokinetic/Pharmacodynamic Approach

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recommendations! Published in 2022 at "Blood Purification"

DOI: 10.1159/000524457

Abstract: Introduction: The Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100) is a hemoperfusion device that can remove pathogens from central circulation. However, the effect of Seraph 100 on achieving pharmacodynamic (PD) targets is not well… read more here.

Keywords: clearance; effect; microbind affinity; 100 microbind ... See more keywords

Seraph 100 Hemoperfusion for Management of Severe COVID-19: Assessment of Serum and Plasma Analytes Pre- and Post-Filtration

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recommendations! Published in 2024 at "Blood Purification"

DOI: 10.1159/000542995

Abstract: Abstract Introduction: We report an Intervention/outcome study of 33 severe COVID-19 subjects who received Seraph 100 Microbind Affinity Blood Filter (Seraph 100) hemoperfusion therapy (15 survivors, 18 non-survivors) under emergency authorization from the FDA. Our… read more here.

Keywords: severe covid; hemoperfusion; 100 hemoperfusion; seraph 100 ... See more keywords

Staphylococcus aureus binding to Seraph® 100 Microbind® Affinity Filter: Effects of surface protein expression and treatment duration

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recommendations! Published in 2023 at "PLOS ONE"

DOI: 10.1371/journal.pone.0283304

Abstract: Introduction Extracorporeal blood purification systems represent a promising alternative for treatment of blood stream infections with multiresistant bacteria. Objectives The aim of this study was to analyse the binding activity of S. aureus to Seraph… read more here.

Keywords: binding activity; affinity; plasma; blood ... See more keywords

The Seraph 100® Microbind Affinity Blood Filter Does Not Alter Levels of Circulating or Mucosal Antibodies in Critical COVID-19 Patients

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recommendations! Published in 2024 at "Antibodies"

DOI: 10.3390/antib13030065

Abstract: PURIFY-OBS-1 is an observational study evaluating the safety and efficacy of Seraph 100® Microbind Affinity Blood Filter (Seraph 100) use for COVID-19 patients with respiratory failure admitted to the intensive care unit (ICU). The Seraph… read more here.

Keywords: filter; levels circulating; seraph 100; 100 microbind ... See more keywords