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   Articles with "serca function" as a keyword



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Novel Approach to Study SERCA Function In Situ

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recommendations! Published in 2017 at "Biophysical Journal"

DOI: 10.1016/j.bpj.2016.11.2165

Abstract: Previously used techniques to measure the sarcoplasmic/endoplasmic reticulum Ca-ATPase (SERCA) function either are cell destructive or lack sensitivity. We designed a new approach that allows studying SERCA function in the cellular environment under well-controlled conditions.… read more here.

Keywords: serca function; cells expressing; study; serca2a ... See more keywords
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Voluntary wheel running and lithium supplementation improves muscle force production without altering SERCA function in the D2 mdx mouse

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recommendations! Published in 2023 at "Physiology"

DOI: 10.1152/physiol.2023.38.s1.5730580

Abstract: Background: Duchenne muscular dystrophy (DMD) is an X-linked recessive muscle wasting disease that, with no cure, leads to early mortality (30-40 years of age). Previous studies have shown that voluntary wheel running can mitigate disease… read more here.

Keywords: serca function; mdx; muscle; physiology ... See more keywords
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SERCA2a tyrosine nitration coincides with impairments in maximal SERCA activity in left ventricles from tafazzin‐deficient mice

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recommendations! Published in 2019 at "Physiological Reports"

DOI: 10.14814/phy2.14215

Abstract: The sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) is imperative for normal cardiac function regulating both muscle relaxation and contractility. SERCA2a is the predominant isoform in cardiac muscles and is inhibited by phospholamban (PLN). Under conditions of oxidative… read more here.

Keywords: serca2a tyrosine; serca function; tyrosine nitration; mice ... See more keywords
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Characterizing SERCA Function in Murine Skeletal Muscles after 35–37 Days of Spaceflight

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recommendations! Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222111764

Abstract: It is well established that microgravity exposure causes significant muscle weakness and atrophy via muscle unloading. On Earth, muscle unloading leads to a disproportionate loss in muscle force and size with the loss in muscle… read more here.

Keywords: murine skeletal; serca function; muscle; ca2 ... See more keywords