Discovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity.
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DOI: 10.1021/acsmedchemlett.7b00222
Abstract: The phosphoinositide 3-kinase (PI3K) inhibitors potently inhibit the signaling pathway of PI3K/AKT/mTOR, which provides a promising new approach for the molecularly targeted cancer therapy. In this work, a novel series of 7-azaindole scaffold derivatives was… read more here.
Keywords: series azaindole; novel series; azaindole scaffold; activity ... See more keywords