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Published in 2023 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.122.001190
Abstract: Among the basic hepatic clearance models, the dispersion model (DM) is the most physiologically sound compared with the well-stirred model and the parallel tube model. However, its application in physiologically-based pharmacokinetic (PBPK) modeling has been…
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Keywords:
hepatic elimination;
clint;
scm;
compartment models ... See more keywords