Articles with "series dianilinopyrimidines" as a keyword



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Design, synthesis and biological evaluation of a series of dianilinopyrimidines as EGFR inhibitors

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Published in 2022 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2022.2046567

Abstract: Abstract This paper described our efforts to develop dianilinopyrimidines as novel EGFR inhibitors. All the target compounds were tested for inhibitory effects against wild type EGFR (EGFRwt) and three tumour cells, including A549, PC-3, and… read more here.

Keywords: design synthesis; synthesis biological; series dianilinopyrimidines; biological evaluation ... See more keywords