New series of 4,6-diaryl pyrimidines: facile synthesis and antiproliferative activity as dual EGFR/VEGFR-2 inhibitors
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DOI: 10.3389/fchem.2024.1498104
Abstract: Introduction We developed and produced a new series of 4,6-diaryl-pyrimidines 9–29 as antiproliferative agents targeting EGFR/VEGFR-2. Methods The antiproliferative efficacy of the novel targets was assessed against a panel of 60 NCI cancer cell lines… read more here.
Keywords: series diaryl; new series; diaryl pyrimidines; vegfr ... See more keywords