Articles with "series flavopiridol" as a keyword



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Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency.

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Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.112355

Abstract: In this work, unique flavopiridol analogs bearing thiosugars, amino acids and heterocyclic moieties tethered to the flavopiridol via thioether and amine bonds mainly on its C ring have been prepared. The analogs bearing thioether-benzimidazoles as… read more here.

Keywords: identification new; cytotoxic; flavopiridol like; series flavopiridol ... See more keywords