Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors.
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DOI: 10.1016/j.ejmech.2019.01.057
Abstract: Protein tyrosine phosphatase 1B (PTP1B) has been considered as a validated biological target for type 2 diabetes treatment, but past endeavors to develop inhibitors of PTP1B into drugs have been unsuccessful. Two challenging aspects are… read more here.
Keywords: compound could; ptp1b; compound; new series ... See more keywords