Novel series of triazole containing coumarin and isatin based hybrid molecules as acetylcholinesterase inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.131085
Abstract: Abstract Novel series of coumarin-triazole and isatin-triazole hybrids were rationally designed, synthesized and biologically evaluated to check their inhibitory potential against acetylcholinesterase enzyme by using in vitro Ellman's method. Most of the hybrid compounds showed… read more here.
Keywords: acetylcholinesterase inhibitors; novel series; coumarin; series triazole ... See more keywords
The Design and Synthesis of a New Series of 1,2,3-Triazole-Cored Structures Tethering Aryl Urea and Their Highly Selective Cytotoxicity toward HepG2
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DOI: 10.3390/ph15050504
Abstract: Target cancer drug therapy is an alternative treatment for advanced hepatocellular carcinoma (HCC) patients. However, the treatment using approved targeted drugs has encountered a number of limitations, including the poor pharmacological properties of drugs, therapy… read more here.
Keywords: cored structures; triazole cored; series triazole; new series ... See more keywords