Interaction of SERINC5 and IFITM1/2/3 regulates the autophagy-apoptosis-immune network under CSFV infection
Sign Up to like & getrecommendations! Published in 2022 at "Virulence"
DOI: 10.1080/21505594.2022.2127241
Abstract: ABSTRACT The host restriction factor serine incorporator 5 (SERINC5) plays a key role in inhibiting viral activity and has been shown to inhibit classical swine fever virus (CSFV) infection. However, the action of SERINC5 in… read more here.
Keywords: serinc5; interaction serinc5; ifitm1; csfv infection ... See more keywords
SERINC5 Potently Restricts Retrovirus Infection In Vivo
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DOI: 10.1128/mbio.00588-20
Abstract: This study examined for the first time the in vivo function of the serine incorporator (SERINC) proteins during retrovirus infection. SERINC3 and SERINC5 (SERINC3/5) restrict a number of retroviruses, including human immunodeficiency virus 1 (HIV-1)… read more here.
Keywords: retrovirus infection; function; vivo; virus ... See more keywords
SERINC5 restricts influenza virus infectivity
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DOI: 10.1371/journal.ppat.1010907
Abstract: SERINC5 is a multi-span transmembrane protein that is incorporated into HIV-1 particles in producing cells and inhibits HIV-1 entry. Multiple retroviruses like HIV-1, equine infectious anemia virus and murine leukemia virus are subject to SERINC5… read more here.
Keywords: serinc5; serinc5 restriction; restricts influenza; serinc5 restricts ... See more keywords
SARS-CoV-2-encoded small RNAs are able to repress the host expression of SERINC5 to facilitate viral replication
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1066493
Abstract: Serine incorporator protein 5 (SERINC5) is a key innate immunity factor that operates in the cell to restrict the infectivity of certain viruses. Different viruses have developed strategies to antagonize SERINC5 function but, how SERINC5… read more here.
Keywords: serinc5; expression serinc5; infection; cov encoded ... See more keywords