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Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.01.084
Abstract: Serine hydroxymethyltransferase (SHMT) catalyzes the interconversion of serine and glycine, which is crucial for one carbon metabolism. Here, we report the first crystal structure of cytoplasmic SHMT from Pichia pastoris (pcSHMT) diffracted to 2.5 Å resolution…
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Keywords:
serine hydroxymethyltransferase;
pichia pastoris;
pastoris;
structure ... See more keywords
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Published in 2017 at "Plant Physiology"
DOI: 10.1104/pp.17.00553
Abstract: A soybean serine hydroxymethyltransferase has a unique and essential role in soybean cyst nematode resistance. Rhg4 is a major genetic locus that contributes to soybean cyst nematode (SCN) resistance in the Peking-type resistance of soybean…
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Keywords:
nematode;
serine hydroxymethyltransferase;
resistance;
gmshmt08 ... See more keywords
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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0208850
Abstract: Serine hydroxymethyltransferase (SHMT), encoded by the glyA gene, is a ubiquitous pyridoxal 5’-phosphate (PLP)-dependent enzyme that catalyzes the formation of glycine from serine. The thereby generated 5,10-methylene tetrahydrofolate (MTHF) is a major source of cellular…
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Keywords:
thyx;
serine hydroxymethyltransferase;
shmt;
functional insight ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22041781
Abstract: Cold-adapted enzymes feature a lower thermostability and higher catalytic activity compared to their warm-active homologues, which are considered as a consequence of increased flexibility of their molecular structures. The complexity of the (thermo)stability-flexibility-activity relationship makes…
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Keywords:
mechanism;
molecular dynamics;
cold adaptation;
serine hydroxymethyltransferase ... See more keywords
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Published in 2020 at "Vaccines"
DOI: 10.3390/vaccines8030349
Abstract: Resistance to soybean cyst nematodes (SCN) in “Peking-type” resistance is bigenic, requiring Rhg4-a and rhg1-a. Rhg4-a encodes a serine hydroxymethyltransferase (GmSHMT08) and rhg1-a encodes a soluble NSF attachment protein (GmSNAP18). Recently, it has been shown…
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Keywords:
protein;
soluble nsf;
serine hydroxymethyltransferase;
nsf attachment ... See more keywords
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Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.12943
Abstract: Serine hydroxymethyltransferase (SHMT) is one of the most important enzyme families in one-carbon metabolic pathway and photorespiration within plant cells. Recently studies reported the active roles of plant SHMTs in defending abiotic stresses. However, genome-scale…
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Keywords:
serine hydroxymethyltransferase;
genome wide;
analysis;
hydroxymethyltransferase shmt ... See more keywords