Serine Metabolism Regulates YAP Activity Through USP7 in Colon Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.639111
Abstract: Metabolic reprogramming is a vital factor in the development of many types of cancer, including colon cancer. Serine metabolic reprogramming is a major feature of tumor metabolism. Yes-associated protein (YAP) participates in organ size control… read more here.
Keywords: cancer; colon cancer; serine metabolism; colon ... See more keywords
The role of serine metabolism in lung cancer: From oncogenesis to tumor treatment
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1084609
Abstract: Metabolic reprogramming is an important hallmark of malignant tumors. Serine is a non-essential amino acid involved in cell proliferation. Serine metabolism, especially the de novo serine synthesis pathway, forms a metabolic network with glycolysis, folate… read more here.
Keywords: tumor treatment; serine metabolism; metabolism; lung cancer ... See more keywords
SHMT2 regulates serine metabolism to promote the progression and immunosuppression of papillary renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.914332
Abstract: Recent research has demonstrated the diverse relationship between tumour metabolism and the tumour microenvironment (TME), for example, abnormal serine metabolism. This study investigated the role of serine metabolism in papillary renal cell carcinoma (pRCC) focusing… read more here.
Keywords: metabolism; cell; serine metabolism; expression ... See more keywords
Serine Metabolism in Health and Disease and as a Conditionally Essential Amino Acid
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14091987
Abstract: L-serine plays an essential role in a broad range of cellular functions including protein synthesis, neurotransmission, and folate and methionine cycles and synthesis of sphingolipids, phospholipids, and sulphur containing amino acids. A hydroxyl side-chain of… read more here.
Keywords: serine metabolism; essential amino; serine; conditionally essential ... See more keywords