A serine protease-associated lectin in the cytolytic system of blowfly (Chrysomya megacephala) larvae: Evidence and characterization.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21623
Abstract: Cytolytic activity against invading microorganisms is one of the innate forms of immunity in invertebrates. A serine protease-associated sialic acid-specific cytolytic lectin was purified using glutaraldehyde-fixed ox erythrocytes from the larval extract of blowfly (Chrysomya… read more here.
Keywords: serine protease; lectin; protease associated; blowfly ... See more keywords
Identification and expression profiling of serine protease-related genes in Tenebrio molitor.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of insect biochemistry and physiology"
DOI: 10.1002/arch.21963
Abstract: In insects, serine proteases and serine protease homologs (SPs/SPHs) are involved in a variety of physiological processes including digestion, development, and immunity. Here, we identified 112 SP and 88 SPH genes in the genome of… read more here.
Keywords: molitor; serine protease; sps sphs; expression ... See more keywords
Fabrication of silver chloride nanoparticles using a plant serine protease in combination with photoactivation and investigation of their biological activities
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1638
Abstract: Recently, the development of "green" methods for fabrication of silver nanoparticles (Ag‐NPs) has been emphasized, in view of their environmental safety, feasibility, and low cost. In this study, a serine protease, EuP‐82 from Euphorbia cf.… read more here.
Keywords: serine protease; chloride nanoparticles; fabrication silver; silver chloride ... See more keywords
The Structure‐Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200186
Abstract: Human bleomycin hydrolase (hBH) catalyzes deamidation of the anticancer drug bleomycins (BLM). This enzyme is involved in BLM detoxification and drug resistance. Herein, we report the putative BLM‐binding site and catalytic mechanism of hBH. The… read more here.
Keywords: protease; cysteine protease; serine protease; bleomycin hydrolase ... See more keywords
KLK14 interactions with HAI‐1 and HAI‐2 serine protease inhibitors: A molecular dynamics and relative free‐energy calculations study
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10839
Abstract: Kallikrein 14 (KLK14) is a serine protease linked to several pathologies including prostate cancer and positively correlates with Gleason score. Though KLK14 functioning in cancer is poorly understood, it has been implicated in HGF/Met signaling,… read more here.
Keywords: hai hai; energy calculations; serine protease; hai ... See more keywords
Canonical or noncanonical? Structural plasticity of serine protease‐binding loops in Kunitz‐STI protease inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Protein Science"
DOI: 10.1002/pro.4570
Abstract: The Kunitz‐Soybean Trypsin Inhibitor (Kunitz‐STI) family is a large family of proteins with most of its members being protease inhibitors. The versatility of the inhibitory profile and the structural plasticity of these proteins, make this… read more here.
Keywords: binding loops; protease; kunitz sti; serine protease ... See more keywords
Detection of Protein Uptake in In Vitro Cultured Astrocytes Exemplified by the Uptake of the Serine Protease, Tissue Plasminogen Activator.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9068-9_14
Abstract: Astrocytes are heterogeneous cells of the central nervous system whose uptake of neurotransmitters and neuromodulators can influence synaptic signaling. Any malfunction in this process can lead to serious defects in synaptic transmission found in, for… read more here.
Keywords: serine protease; cultured astrocytes; vitro cultured; plasminogen activator ... See more keywords
Serine Protease Inhibitors to Treat Lung Inflammatory Diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-68748-9_13
Abstract: Lung is a vital organ that ensures breathing function. It provides the essential interface of air filtering providing oxygen to the whole body and eliminating carbon dioxide in the blood; because of its exposure to… read more here.
Keywords: treat lung; serine protease; inflammatory; protease inhibitors ... See more keywords
In Silico Study of Alkaline Serine Protease and Production Optimization in Bacillus sp. Khoz1 Closed Bacillus safensis Isolated from Honey
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-020-10016-8
Abstract: Protease is a kind of enzyme with different applications in medicine and industry. The limitation of the enzymes in industry is lack of tolerance for harsh conditions (high temperature, pH, and low water condition). This… read more here.
Keywords: alkaline serine; production; protease; serine protease ... See more keywords
A critical review on serine protease: Key immune manipulator and pathology mediator
Sign Up to like & getrecommendations! Published in 2017 at "Allergologia et Immunopathologia"
DOI: 10.1016/j.aller.2016.10.011
Abstract: Abstract Proteolytic activity is fundamental to survival, so it is not surprising that all living organisms have proteases, especially seine protease. This enzyme in its numerous isoforms and homologues, constitutes the quintessential offence and defence… read more here.
Keywords: serine protease; critical review; protease; pathology ... See more keywords
Biochemical and thermodynamic characteristics of a new serine protease from Mucor subtilissimus URM 4133
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Reports"
DOI: 10.1016/j.btre.2020.e00552
Abstract: Graphical abstract Highlights • A protease from Mucor subtilissimus URM 4133, capable of producing bioactive peptides from goat casein, was purified.• Analysis by SDS-PAGE and zymography, shown a molecular mass of approximately 30 kDa.• Purified… read more here.
Keywords: protease mucor; subtilissimus urm; serine protease; mucor subtilissimus ... See more keywords