Purification and Characterization of Serum Serpin from Carp (Cyprinus carpio)
Sign Up to like & getrecommendations! Published in 2017 at "Marine Biotechnology"
DOI: 10.1007/pl00011755
Abstract: Abstract A serine proteinase inhibitor, termed serpin62, was purified to homogeneity from carp serum with an increase in specific inhibitory activity of 6.2-fold and a 3% recovery rate after separation from α1-antitrypsin. Specific inhibitory activity… read more here.
Keywords: activity; serum; characterization serum; serine proteinase ... See more keywords
A snake‐like serine proteinase (PmSnake) activates prophenoloxidase‐activating system in black tiger shrimp Penaeus monodon
Sign Up to like & getrecommendations! Published in 2017 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2016.09.016
Abstract: ABSTRACT Clip domain serine proteinases (ClipSPs) play critical roles in the activation of proteolytic cascade in invertebrate immune systems including the prophenoloxidase (proPO) activating system. In this study, we characterized a snake‐like serine protease, namely… read more here.
Keywords: system; shrimp; like serine; serine proteinase ... See more keywords
Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103871
Abstract: Kazal-type serine proteinase inhibitors (KPIs) function in physiological and immunological processes requiring proteinase action. In the present study, the first Cherax quadricarinatus KPI gene (designated CqKPI) was identified and characterized. The open reading frame of… read more here.
Keywords: kazal type; type serine; cqkpi; proteinase ... See more keywords
Caesalpinia bonduc serine proteinase inhibitor CbTI-2: Exploring the conformational features and antimalarial activity.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.044
Abstract: Seeds of tropical legumes posses a repertoire of proteinase inhibitors (PI) and the current study highlights some structural/functional features of a strong serine PI from the seeds of Caesalpinia bonduc (CbTI-2). Following purification, N-terminal sequence… read more here.
Keywords: caesalpinia bonduc; cbti; bonduc serine; serine proteinase ... See more keywords
Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2018.12.003
Abstract: Reversible serine proteinase inhibitors comprise 18 unrelated families. Each family has a distinct representative structure but contains a surface loop that adopts the same, canonical conformation in the enzyme-inhibitor complex. The Laskowski mechanism universally applies… read more here.
Keywords: proteinase inhibitors; additivity; interscaffolding additivity; loop ... See more keywords