Articles with "seroclearance" as a keyword



Long‐term outcomes and predictive scores for hepatocellular carcinoma and hepatitis B surface antigen seroclearance after hepatitis B e‐antigen seroclearance

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Published in 2018 at "Hepatology"

DOI: 10.1002/hep.29874

Abstract: The significance of hepatitis B e‐antigen (HBeAg) seroclearance (ESC) in the long term is not well defined. The current study aimed to determine the clinical outcomes, the factors and predictive scores for hepatocellular carcinoma (HCC),… read more here.

Keywords: hepatitis; esc; antigen; predictive scores ... See more keywords

Circulating microRNA‐122 levels are important predictor of hepatitis B virus surface antigen seroclearance

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Published in 2018 at "Journal of Medical Virology"

DOI: 10.1002/jmv.25238

Abstract: It is currently unclear what impact serum microRNA‐122 (miR‐122) levels have on clearance of hepatitis B virus (HBV) surface antigen (HBsAg) in HBV‐infected patients who had not received antiviral therapy. The current study evaluated the… read more here.

Keywords: antigen; mir 122; serum mir; seroclearance ... See more keywords

Anti-HBc IgG Levels: A Predictor of HBsAg Seroclearance in Chronic Hepatitis B Patients with Nucleos(t)ide Analogue-Induced HBeAg Seroclearance

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Published in 2021 at "Digestive Diseases and Sciences"

DOI: 10.1007/s10620-021-06845-2

Abstract: We investigated the efficiency of the indirect ratio of anti-HBc IgG at predicting HBsAg seroclearance in patients with nucleos(t)ide analogue (NA)-induced HBeAg seroclearance. We performed a retrospective study that included 366 chronic hepatitis B patients… read more here.

Keywords: seroclearance; anti hbc; hbc igg; hbsag seroclearance ... See more keywords
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Durability of hepatitis B surface antigen seroclearance in untreated and nucleos(t)ide analogue-treated patients.

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Published in 2017 at "Journal of hepatology"

DOI: 10.1016/j.jhep.2017.09.018

Abstract: BACKGROUND & AIMS It is uncertain if nucleos(t)ide analogue (NA)-induced hepatitis B surface antigen (HBsAg) seroclearance is durable. We investigated the impact of hepatitis B surface antibody (anti-HBs) and duration of consolidation antiviral therapy on… read more here.

Keywords: hepatitis surface; seroclearance; nucleos ide; hbsag seroclearance ... See more keywords

Factors Associated With Rates of HBsAg Seroclearance in Adults With Chronic HBV Infection: A Systematic Review and Meta-analysis.

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Published in 2019 at "Gastroenterology"

DOI: 10.1053/j.gastro.2018.10.027

Abstract: BACKGROUND & AIMS Seroclearance of hepatitis B surface antigen (HBsAg) is a marker for clearance of chronic hepatitis B virus (HBV) infection, but reported annual incidence rates of HBsAg seroclearance vary. We performed a systematic… read more here.

Keywords: hbv infection; seroclearance; systematic review; hbsag seroclearance ... See more keywords

A scoring system to predict HBsAg seroclearance in hepatitis B and C coinfected patients treated with interferon and ribavirin in an Asian cohort

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Published in 2018 at "Medicine"

DOI: 10.1097/md.0000000000013383

Abstract: Abstract Current guidelines recommend that patients with hepatitis B virus-hepatitis C virus (HBV-HCV) coinfection be treated with direct anti-viral agents (DAAs). Compared with DAAs, pegylated interferon (PEG-IFN) and ribavirin therapy has the advantages of treating… read more here.

Keywords: risk; ribavirin; scoring system; cohort ... See more keywords

Spontaneous Hepatitis B Seroclearance upon Development of Hepatocellular Carcinoma

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Published in 2017 at "Case Reports in Gastroenterology"

DOI: 10.1159/000484660

Abstract: The spontaneous seroclearance of hepatitis B upon development of a hepatocellular carcinoma (HCC) is extremely rare. To date, there has been one published case series reporting hepatitis B seroconversion following HCC resection. We describe two… read more here.

Keywords: hepatocellular carcinoma; hepatitis; development hepatocellular; seroclearance ... See more keywords

Preoperative HBsAg seroclearance affects long-term outcomes for hepatitis B virus-related hepatocellular carcinoma after liver resection: a multicenter analysis

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Published in 2025 at "BMC Cancer"

DOI: 10.1186/s12885-025-14869-4

Abstract: We aimed to investigate the impact of HBsAg seroclearance on the long-term prognosis of HBV-related HCC following curative liver resection. Patients treated with curative-intent hepatectomy for HBV-related HCC in 4 Chinese hospitals were enrolled. Patients… read more here.

Keywords: seroclearance; long term; hbsag seroclearance; related hcc ... See more keywords

Risk of hepatocellular carcinoma after spontaneous and nucleos(t)ide analogue induced hepatitis B surface antigen seroclearance.

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Published in 2021 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2021.39.15_suppl.e16162

Abstract: e16162 Background: Despite a favorable clinical course, the risk of hepatocellular carcinoma (HCC) still exists in patients achieving HBsAg seroclearance. Therefore, we investigated the incidence of HCC after spontaneous and nucleos(t)ide analogue (NA) induced HBsAg… read more here.

Keywords: induced hbsag; hcc; incidence; seroclearance ... See more keywords

Rapid decline rather than absolute level of HBsAg predicts its seroclearance in untreated chronic hepatitis B patients from Taiwanese communities.

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Published in 2023 at "Clinical and translational gastroenterology"

DOI: 10.14309/ctg.0000000000000586

Abstract: ABSTRACT BackgroundHBsAg clearance leads to favorable outcomes in chronic hepatitis B (CHB) patients. Hepatitis B surface antigen (HBsAg) levels 0.5 log10 IU/mL in one year have been reported predictive of HBsAg loss. This study aimed… read more here.

Keywords: decline; year; hbsag; hbsag decline ... See more keywords

Metabolic-Associated Fatty Liver Disease, Hepatitis B Surface Antigen Seroclearance, and Long-Term Risk of Hepatocellular Carcinoma in Chronic Hepatitis B

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Published in 2022 at "Cancers"

DOI: 10.3390/cancers14236012

Abstract: Simple Summary Concomitant hepatic steatosis is common in patients with chronic hepatitis B (CHB), but data regarding its impact on the natural history of CHB remain sparse and conflicting. Recently, metabolic-associated fatty liver disease (MAFLD)… read more here.

Keywords: chb; hcc; risk; hepatitis ... See more keywords