Evaluation of three commercial SARS-CoV-2 serology assays in a tertiary care hospital in the United Arab Emirates
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Infection and Public Health"
DOI: 10.1016/j.jiph.2021.04.003
Abstract: Background Serology assays have the potential to support RT-PCR in the diagnosis of SARS-CoV-2 infection. We studied three commercially available immunoassays for their diagnostic accuracy from blood specimens collected from 93 patients. Methods Blood samples… read more here.
Keywords: serology; infection; collected days; serology assays ... See more keywords
Standardization of two SARS-CoV-2 serology assays to the WHO 20/136 human standard reference material
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virological Methods"
DOI: 10.1016/j.jviromet.2021.114430
Abstract: WHO 20/136 is standard reference material for SARS-CoV-2 serology assays. Standardization of serology assays that target the same antigen and class of immunoglobulin will enable comparison of results between studies that use various lab-developed and… read more here.
Keywords: sars cov; serology; reference material; standard reference ... See more keywords
Validation of monoplex assays detecting antibodies against Corynebacterium diphtheriae and Clostridium tetani toxins, rubella virus and parvovirus B19 for incorporation into Multiplex Serology.
Sign Up to like & getrecommendations! Published in 2019 at "Methods"
DOI: 10.1016/j.ymeth.2019.01.013
Abstract: Serological assays detecting antibodies in serum or plasma samples are useful and versatile instruments to investigate an individual's infection and vaccination history, e.g. for clinical diagnosis, personal risk evaluation, and seroepidemiological studies. Multiplex Serology is… read more here.
Keywords: multiplex serology; detecting antibodies; assays detecting; serology ... See more keywords
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
Sign Up to like & getrecommendations! Published in 2020 at "Nature Biotechnology"
DOI: 10.1038/s41587-020-0659-0
Abstract: Appropriate use and interpretation of serological tests for assessments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure, infection and potential immunity require accurate data on assay performance. We conducted a head-to-head evaluation of ten… read more here.
Keywords: serology; time; evaluation; serology assays ... See more keywords
Setting Bias Specifications Based on Qualitative Assays With a Quantitative Cutoff Using COVID-19 as a Disease Model
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Clinical Pathology"
DOI: 10.1093/ajcp/aqac072
Abstract: Abstract Objectives Automated qualitative serology assays often measure quantitative signals that are compared against a manufacturer-defined cutoff for qualitative (positive/negative) interpretation. The current general practice of assessing serology assay performance by overall concordance in a… read more here.
Keywords: qualitative assays; serology; disease; bias specifications ... See more keywords
Assay Harmonization Study To Measure Immune Response to SARS-CoV-2 Infection and Vaccines: a Serology Methods Study
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.05353-22
Abstract: Previous studies have shown significant variability in SARS-CoV-2 antibody serology assays, highlighting the need for evaluation and comparison of these assays using the same set of samples covering a wide range of antibody responses induced… read more here.
Keywords: serology; infection; serology assays; sars cov ... See more keywords