β-Catenin Role in the Vulnerability/Resilience to Stress-Related Disorders Is Associated to Changes in the Serotonergic System
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-01841-0
Abstract: We previously reported that the inactivation (cKO) or the stabilization (cST) of β-catenin in cells expressing the astrocyte-specific glutamate aspartate transporter (GLAST) is associated with the vulnerability or resilience to exhibit anxious/depressive-like behaviors, respectively, and… read more here.
Keywords: functionality; stress; vulnerability resilience; serotonergic system ... See more keywords
Serotonergic system, cognition, and BPSD in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.03.050
Abstract: Behavioral and Psychological Symptoms of Dementia (BPSD), present in almost 90% of patients with Alzheimer's Disease (AD), cause extensive impairment leading to reduced independence and inability to complete activities of daily living. Though BPSD includes… read more here.
Keywords: cognition bpsd; alzheimer disease; disease; system cognition ... See more keywords
The role of the serotonergic system in motor control
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Research"
DOI: 10.1016/j.neures.2017.07.005
Abstract: The serotonergic system in the vertebrate brain is implicated in various behaviors and diseases. Its involvement in motor control has been studied for over half a century, but efforts to build a unified model of… read more here.
Keywords: motor control; system; system motor; serotonergic system ... See more keywords
The pharmacological and functional characterization of the serotonergic system in Anopheles gambiae and Aedes aegypti: influences on flight and blood-feeding behavior
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38806-1
Abstract: Aedes aegypti and Anopheles gambiae harbor the causative agents of diseases such as dengue fever and malaria, afflicting human morbidity and mortality worldwide. Given the worldwide emergence of resistance to insecticides, the current mainstay for… read more here.
Keywords: aedes aegypti; system; feeding behavior; blood feeding ... See more keywords
Serotonergic system may be involved in alterations of sleep homeostasis in spontaneously hypertensive rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Sleep Research"
DOI: 10.1111/jsr.12947
Abstract: Hypertension is associated with sleep disorders. Spontaneously hypertensive rats are derived from Wistar‐Kyoto rats and widely used in research on hypertension. The present study investigated the propensity to sleep and electroencephalographic spectrum changes over 24… read more here.
Keywords: sleep homeostasis; spontaneously hypertensive; hypertensive rats; homeostasis spontaneously ... See more keywords
Alternative splicing in serotonergic system: Implications in neuropsychiatric disorders
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881119856546
Abstract: Background: The serotonergic system is a key component of physiological brain function and is essential for proper neurological activity. Numerous neuropsychiatric disorders are associated with deregulation of the serotonergic system. Accordingly, many pharmacological treatments are… read more here.
Keywords: system; splicing serotonergic; alternative splicing; neuropsychiatric disorders ... See more keywords
The serotonergic system dysfunction in diabetes mellitus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.899069
Abstract: Most peripheral serotonin (5-HT) is synthesized in enterochromaffin cells, and most circulating 5-HT is stored in platelets. As a monoamine, 5-HT has several functions in various non-neuronal and neuronal systems. In the central nervous system,… read more here.
Keywords: system; serotonergic system; diabetes mellitus; system dysfunction ... See more keywords
Latest updates on the serotonergic system in depression and anxiety
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2023.1124112
Abstract: Psychiatric disorders are among the leading causes of global health burden, with depression and anxiety being the most disabling subtypes. The two common disorders, depression and anxiety, usually coexist and are pathologically polygenic with complicated… read more here.
Keywords: anxiety; system depression; serotonergic system; depression anxiety ... See more keywords
Intensity-Dependence of Auditory Evoked Potentials (IDAP) as a Neurophysiological Parameter to Predict Anti-Aggressive Responsiveness to SSRI Treatment
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.716338
Abstract: The rationale for selective serotonin reuptake inhibitor (SSRI) treatment in patients with aggressive behavior comes from several studies aimed at comprehending the neurobiological basis of anger and aggression and, in particular, at investigating the involvement… read more here.
Keywords: aggressive behavior; aggression; ssri treatment; intensity dependence ... See more keywords
Melatonin Reduces Alcohol Drinking in Rats with Disrupted Function of the Serotonergic System
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12030355
Abstract: The reason for the limited treatment success of substance-use-related problems may be a causal heterogeneity of this disorder that, at least partly, is manifested as differences in substance-use motives between individuals. The aim of the… read more here.
Keywords: serotonergic; treatment; function serotonergic; serotonergic system ... See more keywords