Brain-wide Mapping of Endogenous Serotonergic Transmission via Chemogenetic fMRI.
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.09.087
Abstract: Serotonin-producing neurons profusely innervate brain regions via long-range projections. However, it remains unclear whether and how endogenous serotonergic transmission specifically influences regional or global functional activity. We combined designed receptors exclusively activated by designed drugs (DREADD)-based chemogenetics… read more here.
Keywords: serotonergic transmission; serotonin; brain wide; endogenous serotonergic ... See more keywords
Serotonergic transmission plays differentiated roles in the rapid and sustained antidepressant‐like effects of ketamine
Sign Up to like & getrecommendations! Published in 2024 at "British Journal of Pharmacology"
DOI: 10.1111/bph.17324
Abstract: The emerging antidepressant effects of ketamine have inspired tremendous interest in its underlying neurobiological mechanisms, although the involvement of 5‐HT in the antidepressant effects of ketamine remains unclear. read more here.
Keywords: effects ketamine; differentiated roles; plays differentiated; roles rapid ... See more keywords