TARGETED METABOLOMICS IDENTIFIES ELEVATED SEROTONIN LEVELS IN CARRIERS OF A TCF7L2 DIABETES-RISK ALLELE
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)32725-1
Abstract: The transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Its polymorphism rs7903146 is associated with risk for metabolic diseases, primarily diabetes, whereas the molecular mechanisms explaining how TCF7L2 impacts metabolism have… read more here.
Keywords: elevated serotonin; levels carriers; metabolomics identifies; serotonin levels ... See more keywords
Lower serotonin levels in severe sleep bruxism and its association with sleep, heart rate, and body mass index.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13295
Abstract: BACKGROUND Sleep bruxism (SB) is a complex behavior that seems to be associated with serotoninergic pathway. OBJECTIVES This exploratory research aimed to evaluate the levels of serotonin in individuals with sleep bruxism diagnosed by video… read more here.
Keywords: sleep bruxism; mass index; bruxism; body mass ... See more keywords
Circulating serotonin levels in COPD patients: a pilot study
Sign Up to like & getrecommendations! Published in 2018 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-018-0730-5
Abstract: BackgroundChronic obstructive pulmonary disease (COPD) is a major and increasing global health problem. Serotonin is a neurotransmitter that participates in several pulmonary functions and it has been involved in oxidative stress, which plays essential roles… read more here.
Keywords: serotonin levels; copd patients; circulating serotonin; serotonin ... See more keywords
Serum serotonin levels are elevated in patients with increased risk of rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1081814
Abstract: Background Even though serotonin (5-HT) has been ascribed immunomodulatory features, very little is known about its role in chronic inflammatory diseases. Serotonin is implicated in inflammation and increased levels have been associated with progression of… read more here.
Keywords: serotonin; serotonin levels; arthritis; risk ... See more keywords
Associations of Serum Serotonin Levels with 12-week and 12-month Remission in Patients with Depressive Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2022.20.2.248
Abstract: Objective To investigate associations between baseline serum serotonin levels and short- and long-term treatment outcomes in outpatients with depressive disorders in a naturalistic one-year prospective study design. Methods Patients were recruited at a University hospital… read more here.
Keywords: serotonin levels; remission; depressive disorders; treatment ... See more keywords