TARGETED METABOLOMICS IDENTIFIES ELEVATED SEROTONIN LEVELS IN CARRIERS OF A TCF7L2 DIABETES-RISK ALLELE
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(19)32725-1
Abstract: The transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Its polymorphism rs7903146 is associated with risk for metabolic diseases, primarily diabetes, whereas the molecular mechanisms explaining how TCF7L2 impacts metabolism have… read more here.
Keywords: elevated serotonin; levels carriers; metabolomics identifies; serotonin levels ... See more keywords
Addressing the serotonin hypothesis of depression through analyses of genetics, methylation and metabolite variations in glioma patients
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-25464-9
Abstract: Serotonin and serotonin metabolism has for decades been understood as playing a critical role in mood disorders and has more recently also been implicated in brain tumour biology. However, in part due to the lack… read more here.
Keywords: genetics; methylation; serotonin; maoa ... See more keywords
Circadian variation in plasma serotonin level in equines submitted to transport stress
Sign Up to like & getrecommendations! Published in 2024 at "Biological Rhythm Research"
DOI: 10.1080/09291016.2024.2429845
Abstract: ABSTRACT Stress triggers a set of adaptative reactions that can compromise the homeostasis of the organism, such as transport from one environment to another. The aim of the present study was to determine whether there… read more here.
Keywords: variation; transport stress; plasma serotonin; serotonin ... See more keywords
Lower serotonin levels in severe sleep bruxism and its association with sleep, heart rate, and body mass index.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of oral rehabilitation"
DOI: 10.1111/joor.13295
Abstract: BACKGROUND Sleep bruxism (SB) is a complex behavior that seems to be associated with serotoninergic pathway. OBJECTIVES This exploratory research aimed to evaluate the levels of serotonin in individuals with sleep bruxism diagnosed by video… read more here.
Keywords: sleep bruxism; mass index; bruxism; body mass ... See more keywords
Circulating serotonin levels in COPD patients: a pilot study
Sign Up to like & getrecommendations! Published in 2018 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-018-0730-5
Abstract: BackgroundChronic obstructive pulmonary disease (COPD) is a major and increasing global health problem. Serotonin is a neurotransmitter that participates in several pulmonary functions and it has been involved in oxidative stress, which plays essential roles… read more here.
Keywords: serotonin levels; copd patients; circulating serotonin; serotonin ... See more keywords
Serum serotonin levels are elevated in patients with increased risk of rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1081814
Abstract: Background Even though serotonin (5-HT) has been ascribed immunomodulatory features, very little is known about its role in chronic inflammatory diseases. Serotonin is implicated in inflammation and increased levels have been associated with progression of… read more here.
Keywords: serotonin; serotonin levels; arthritis; risk ... See more keywords
Association Among Depressive Symptoms, Physical Symptoms, Serotonin Levels, and Gambling Disorder: A Case-Control Study.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of psychosocial nursing and mental health services"
DOI: 10.3928/02793695-20250415-03
Abstract: PURPOSE The current study compares depressive symptoms, physical symptoms, and serotonin levels between individuals with gambling disorder (GD) and healthy controls (HC), investigates their relationship, and identifies factors that predict the development of GD. METHOD… read more here.
Keywords: symptoms serotonin; physical symptoms; symptoms physical; depressive symptoms ... See more keywords
Associations of Serum Serotonin Levels with 12-week and 12-month Remission in Patients with Depressive Disorders
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Psychopharmacology and Neuroscience"
DOI: 10.9758/cpn.2022.20.2.248
Abstract: Objective To investigate associations between baseline serum serotonin levels and short- and long-term treatment outcomes in outpatients with depressive disorders in a naturalistic one-year prospective study design. Methods Patients were recruited at a University hospital… read more here.
Keywords: serotonin levels; remission; depressive disorders; treatment ... See more keywords