Articles with "serotonin norepinephrine" as a keyword



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Persistence with selective serotonin (norepinephrine) reuptake inhibitors in Germany-A retrospective database analysis.

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Published in 2019 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2019.01.016

Abstract: INTRODUCTION Selective serotonin (norepinephrine) reuptake inhibitors (SS(N)RIs) are used in the treatment of depression. The aim of this study was to assess the persistence with SS(N)RIs in outpatients treated by general practitioners (GP) or psychiatrists… read more here.

Keywords: selective serotonin; index; serotonin norepinephrine; treatment ... See more keywords
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What Contributes to Serotonin-Norepinephrine Reuptake Inhibitors' Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation.

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Published in 2018 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.7b00490

Abstract: Dual inhibition of serotonin and norepinephrine transporters (hSERT and hNET) gives greatly improved efficacy and tolerability for treating major depressive disorder (MDD) compared with selective reuptake inhibitors. Pioneer studies provided valuable information on structure, function,… read more here.

Keywords: serotonin norepinephrine; norepinephrine transporters; reuptake inhibitors; mechanism ... See more keywords
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Serotonin‐norepinephrine reuptake inhibitors and the influence of binding affinity (Ki) on analgesia

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Published in 2017 at "Journal of Clinical Pharmacy and Therapeutics"

DOI: 10.1111/jcpt.12534

Abstract: Serotonin‐norepinephrine reuptake inhibitors (SNRIs) are commonly used for various psychiatric conditions and neuropathic pain syndromes. SNRIs inhibit the reuptake of serotonin (5‐HT) and norepinephrine (NE); however, NE reuptake inhibition is thought to be the primary… read more here.

Keywords: serotonin norepinephrine; reuptake inhibitors; norepinephrine reuptake; influence binding ... See more keywords