The serotonin reuptake transporter modulates mitochondrial copy number and mitochondrial respiratory complex gene expression in the frontal cortex and cerebellum in a sexually dimorphic manner
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.25010
Abstract: Neuropsychiatric and neurodevelopmental disorders such as major depressive disorder (MDD) and autism spectrum disorder (ASD) are complex conditions attributed to both genetic and environmental factors. There is a growing body of evidence showing that serotonergic… read more here.
Keywords: reduced sert; modulates mitochondrial; transporter; sert expression ... See more keywords
Synergistic anti‐depressive effect of combination treatment of Brexpiprazole and selective serotonin reuptake inhibitors on forced swimming test in mice
Sign Up to like & getrecommendations! Published in 2023 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12316
Abstract: Selective serotonin reuptake inhibitors (SSRIs) are used to treat major depressive disorder (MDD) and other psychiatric disorders (e.g., obsessive compulsive disorder, social anxiety disorder, and panic disorder). In MDD treatment, SSRIs do not show remission… read more here.
Keywords: effect; reuptake inhibitors; selective serotonin; serotonin reuptake ... See more keywords
Risk of Intracranial Hemorrhage Associated with the Use of Antidepressants Inhibiting Serotonin Reuptake: A Systematic Review
Sign Up to like & getrecommendations! Published in 2018 at "CNS Drugs"
DOI: 10.1007/s40263-018-0507-7
Abstract: BackgroundObservational studies have suggested an increased risk of intracranial hemorrhage (ICH) associated with selective serotonin reuptake inhibitors (SSRIs) and other antidepressants primarily inhibiting serotonin reuptake.ObjectivesOur aim was to systematically review the available epidemiologic evidence regarding… read more here.
Keywords: risk ich; risk; serotonin reuptake; inhibiting serotonin ... See more keywords
Comparative transcriptomics implicate mitochondrial and neurodevelopmental impairments in larval zebrafish (Danio rerio) exposed to two selective serotonin reuptake inhibitors (SSRIs).
Sign Up to like & getrecommendations! Published in 2020 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2020.110934
Abstract: Pharmaceuticals and personal care products are emerging contaminants that are increasingly detected in the environment worldwide. Certain classes of pharmaceuticals, such as selective serotonin reuptake inhibitors (SSRIs), are a major environmental concern due to their… read more here.
Keywords: selective serotonin; serotonin reuptake; inhibitors ssris; exposure ... See more keywords
Modeling the acute pharmacological response to selective serotonin reuptake inhibitors in human brain using simultaneous PET/MR imaging
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2019.04.001
Abstract: Pharmacological imaging of the effects of selective serotonin reuptake inhibitors (SSRI) may aid the clarification of their mechanism of action and influence treatment of highly prevalent neuropsychiatric conditions if the detected effects could be related… read more here.
Keywords: selective serotonin; serotonin reuptake; response; pharmacological response ... See more keywords
Effect of Selective Serotonin Reuptake Inhibitor Use in Pregnancy on Emotional Health of Children.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American Academy of Child and Adolescent Psychiatry"
DOI: 10.1016/j.jaac.2018.04.018
Abstract: I read with interest the article by Lupattelli et al., "Effect of Time-Dependent Selective Serotonin Reuptake Inhibitor Antidepressants During Pregnancy on Behavioral, Emotional, and Social Development in Preschool-Aged Children,"1 which describes the effects of selective serotonin… read more here.
Keywords: use pregnancy; selective serotonin; serotonin reuptake; reuptake inhibitor ... See more keywords
Personality, symptom, and demographic correlates of perceived efficacy of selective serotonin reuptake inhibitor monotherapy among current users with low mood: A data-driven approach
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Affective Disorders"
DOI: 10.1016/j.jad.2021.08.088
Abstract: Abstract Background Selective serotonin reuptake inhibitors (SSRIs) are often the first-line treatment option for depressive symptoms, however their efficacy varies across patients. Identifying predictors of response to SSRIs could facilitate personalised treatment of depression and… read more here.
Keywords: selective serotonin; serotonin reuptake; personality symptom; treatment ... See more keywords
Selective serotonin reuptake inhibitors (SSRI) affect murine bone lineage cells.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117827
Abstract: AIMS Data suggest pharmacological treatment of depression with selective serotonin reuptake inhibitors (SSRI) may impair bone health. Our group has previously modeled compromised craniofacial healing after treatment with sertraline, a commonly prescribed SSRI, and hypothesized… read more here.
Keywords: selective serotonin; serotonin reuptake; lineage; treatment ... See more keywords
Selective Serotonin Reuptake Inhibitors and Cataract Risk: A Case-Control Analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2017.05.002
Abstract: PURPOSE Use of selective serotonin reuptake inhibitors (SSRIs) has been associated with an increased cataract risk. We aimed to assess cataract risk after exposure to SSRI or to other antidepressant drugs in a large electronic… read more here.
Keywords: selective serotonin; serotonin reuptake; use; cataract risk ... See more keywords
Impact of selective serotonin reuptake inhibitors on neural crest stem cell formation.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.08.012
Abstract: The use of antidepressants in pregnant women is rising, with rates up to 7.5% in the United States. Selective serotonin reuptake inhibitors (SSRIs) are currently the most common antidepressant prescribed to pregnant women. The teratogenic… read more here.
Keywords: selective serotonin; serotonin reuptake; reuptake inhibitors; stem cell ... See more keywords
Multiple possible inaccuracies cast doubt on a recent report suggesting selective serotonin reuptake inhibitors to be toxic and ineffective
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neuropsychiatrica"
DOI: 10.1017/neu.2017.23
Abstract: According to a systematic review on the use of selective serotonin reuptake inhibitors (SSRIs) in adult depression that was recently published in BMC Psychiatry, the results of which have been widely disseminated in lay media,… read more here.
Keywords: selective serotonin; serotonin reuptake; possible inaccuracies; analysis ... See more keywords