Membrane particles evoke a serotype-independent cross-protection against pneumococcal infection that is dependent on the conserved lipoproteins MalX and PrsA
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DOI: 10.1073/pnas.2122386119
Abstract: Significance Pneumococcal infections are major contributors to morbidity and mortality worldwide. Introduction of pneumococcal conjugated vaccines (PCVs) into the childhood vaccination program has led to a decrease in invasive pneumococcal disease (IPD) in vaccinated children… read more here.
Keywords: protection; membrane particles; evoke serotype; serotype independent ... See more keywords