In search for biomarkers and potential drug targets for uterine serous endometrial cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03566-x
Abstract: Serous endometrial cancer (USC) is a challenging malignancy associated with metastasis, recurrence and poor outcome. To identify clinically relevant prognostic biomarkers, we focused on a panel of proteins selected after a comprehensive literature review, for… read more here.
Keywords: drug targets; biomarkers potential; endometrial cancer; potential drug ... See more keywords
Severe thrombocytopenia after trastuzumab in a patient with HER2-positive serous endometrial cancer.
Sign Up to like & getrecommendations! Published in 2023 at "BMJ case reports"
DOI: 10.1136/bcr-2023-255181
Abstract: Trastuzumab is a humanised, monoclonal antibody that interferes with the human epidermal growth factor receptor 2 (HER2)/neu receptor and binds selectively to the HERB2 protein. It has been shown to prolong survival of patients with… read more here.
Keywords: severe thrombocytopenia; patient; trastuzumab; her2 positive ... See more keywords
Getting serious about serous endometrial cancer: should we give chemotherapy in non-invasive cases?
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2020-001796
Abstract: Recent advances in understanding of risk factors for gastric cancer have focused attention on genetic polymorphisms in both the human host and in Helicobacter pylori. Variation in genes for cytokines such as interleukin-1β and its… read more here.
Keywords: serious serous; gastric cancer; getting serious; endometrial cancer ... See more keywords
Differentiation between serous endometrial cancer and metastatic spread from adnexal cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Cancer"
DOI: 10.1136/ijgc-2021-003326
Abstract: Figure 1 Sections of the specimen showing (A) uterine tumor and (B) right fallopian tumor: highgrade carcinoma feature with complex glandular pattern with a slitlike (C) right ovarian cyst and (D) left ovarian cyst presented… read more here.
Keywords: endometrial cancer; cancer metastatic; cancer differentiation; differentiation serous ... See more keywords
Abstract B018: MYC is sufficient to generate mid-life high-grade serous ovarian and serous endometrial carcinomas in a BRCA wild type p53-R270H mouse model
Sign Up to like & getrecommendations! Published in 2024 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.endo24-b018
Abstract: Genetically engineered mouse models (GEMM) have fundamentally changed how cancer etiology, early detection, and treatment can be understood. Mouse models have been developed that support the fallopian tube as the origin of some ovarian cancers.… read more here.
Keywords: cancer; high grade; p53; grade serous ... See more keywords