Biomarkers expression among paired serous ovarian cancer primary lesions and their peritoneal cavity metastases in treatment‐naïve patients: A single‐center study
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4600
Abstract: High‐grade serous ovarian carcinoma (HGSOC), the most common histologic subtype of ovarian epithelial cancer, is associated with treatment resistance, enhanced recurrence rates, and poor prognosis. HGSOCs often metastasize to the peritoneal cavity, while fluid cytology… read more here.
Keywords: serous ovarian; peritoneal cavity; cytology; treatment ... See more keywords
BDP1 as a biomarker in serous ovarian cancer
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DOI: 10.1002/cam4.5388
Abstract: TFIIIB, an RNA polymerase III specific transcription factor has been found to be deregulated in human cancers with much of the research focused on the TBP, BRF1, and BRF2 subunits. To date, the TFIIIB specific… read more here.
Keywords: bdp1 biomarker; ovarian cancer; serous ovarian; biomarker serous ... See more keywords
Molecular and phenotypic characteristics influencing the degree of cytoreduction in high-grade serous ovarian carcinomas.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6085
Abstract: BACKGROUND High-grade serous ovarian carcinoma (HGSOC) is the deadliest ovarian cancer subtype, and survival relates to initial cytoreductive surgical treatment. The existing tools for surgical outcome prediction remain inadequate for anticipating the outcomes of the… read more here.
Keywords: high grade; grade serous; hgsoc; serous ovarian ... See more keywords
Monitoring the extracellular matrix remodeling of high-grade serous ovarian cancer with nonlinear optical microscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biophotonics"
DOI: 10.1002/jbio.202000498
Abstract: The mortality of high-grade serous ovarian cancer (HGSOC) accounts for 70%-80% of all ovarian cancer deaths and overall mortality rate has not declined in the last decade . Recently, many studies have demonstrated that HGSOC… read more here.
Keywords: serous ovarian; grade serous; high grade; microscopy ... See more keywords
Integrative prognostic subtype discovery in high‐grade serous ovarian cancer
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DOI: 10.1002/jcb.29049
Abstract: We sought to identify novel molecular subtypes of high‐grade serous ovarian cancer (HGSC) by the integration of gene expression and proteomics data and to find the underlying biological characteristics of ovarian cancer to improve the… read more here.
Keywords: serous ovarian; grade serous; high grade; ovarian cancer ... See more keywords
LncRNA LIFR‐AS1 overexpression suppressed the progression of serous ovarian carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24570
Abstract: Serous ovarian carcinoma (SOC) is a common malignant tumor in female reproductive system. Long noncoding RNA (lncRNA) LIFR‐AS1 is a tumor suppressor gene in colorectal cancer, but its effect and underlying mechanism in SOC are… read more here.
Keywords: lifr as1; serous ovarian; lncrna lifr; ovarian carcinoma ... See more keywords
Diffusion‐Weighted Magnetic Resonance Imaging and Morphological Characteristics Evaluation for Outcome Prediction of Primary Debulking Surgery for Advanced High‐Grade Serous Ovarian Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.28418
Abstract: Preoperative assessment of whether a successful primary debulking surgery (PDS) can be performed in patients with advanced high‐grade serous ovarian carcinoma (HGSOC) remains a challenge. A reliable model to precisely predict resectability is highly demanded. read more here.
Keywords: advanced high; high grade; grade serous; primary debulking ... See more keywords
Factors associated with the involvement of lymph nodes in low-grade serous ovarian cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of surgical oncology"
DOI: 10.1002/jso.26700
Abstract: BACKGROUND AND OBJECTIVES Evaluating nodal metastases in low-grade serous ovarian cancer (LGSOC) patients. METHODS Women with LGSOC who had undergone primary cytoreductive surgery comprising systematic pelvic-paraaortic lymphadenectomy were included. Data were obtained retrospectively from 12… read more here.
Keywords: serous ovarian; grade serous; lymph nodes; ovarian cancer ... See more keywords
Differential histone deacetylase inhibitor-induced perturbations of the global proteome landscape in the setting of high-grade serous ovarian cancer
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DOI: 10.1002/pmic.202100372
Abstract: High‐grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy in women. Its low survival rate is attributed to late detection, relapse, and drug resistance. The lack of effective second‐line therapeutics remains a significant… read more here.
Keywords: high grade; grade serous; ovarian cancer; hgsoc ... See more keywords
Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.11.020
Abstract: The high-grade serous ovarian cancer (HGSOC) risk locus at chromosome 1p34.3 resides within a frequently amplified genomic region signifying the presence of an oncogene. Here, we integrate in silico variant-to-function analysis with functional studies to… read more here.
Keywords: cancer; risk; high grade; serous ovarian ... See more keywords
ALPL regulates the aggressive potential of high grade serous ovarian cancer cells via a non-canonical WNT pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.016
Abstract: The ALPL gene is linked to hypophosphatasia, a rare genetic disease. Owing to the inverse relationships between ALPL expression and both the International Federation of Gynecology and Obstetrics (FIGO) stages and histological grades assigned to… read more here.
Keywords: hgsoc; serous ovarian; alpl; wnt ... See more keywords