Electrophoresis- and FRET-Based Measures of Serpin Polymerization.
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DOI: 10.1007/978-1-4939-7163-3_24
Abstract: Many serpinopathies, including alpha-1 antitrypsin (A1AT) deficiency, are associated with the formation of unbranched polymer chains of mutant serpins. In vivo, this deficiency is the result of mutations that cause kinetic or thermodynamic destabilization of… read more here.
Keywords: based measures; polymerization; fret based; electrophoresis fret ... See more keywords