SERPINE2 Overexpression Is Associated with Poor Prognosis of Urothelial Carcinoma
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DOI: 10.3390/diagnostics11101928
Abstract: Recent studies have reported that SERPINE2 contributes to the development of various cancers. However, its association with urothelial carcinoma (UC) remains unclear. In this study, data on urinary bladder UC (UBUC) cases from The Cancer… read more here.
Keywords: poor prognosis; high serpine2; expression; urothelial carcinoma ... See more keywords
LHX2 Enhances the Malignant Phenotype of Esophageal Squamous Cell Carcinoma by Upregulating the Expression of SERPINE2
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DOI: 10.3390/genes13081457
Abstract: LHX2 dysregulations have been found to present in cancers, but the function of LHX2 in esophageal squamous cell carcinoma (ESCC) remains unknown. Here, we report that LHX2 was upregulated in ESCC tissues in comparison to… read more here.
Keywords: cell carcinoma; serpine2; squamous cell; esophageal squamous ... See more keywords
Endocytosis of Peptidase Inhibitor SerpinE2 promotes Myocardial Fibrosis through activating ERK1/2 and β-catenin Signaling Pathways
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DOI: 10.7150/ijbs.67726
Abstract: Cardiac fibrosis is one of the common pathological processes in many cardiovascular diseases characterized by excessive extracellular matrix deposition. SerpinE2 is a kind of protein that inhibits peptidase in extracellular matrix and up-regulated tremendously in… read more here.
Keywords: serpine2; erk1 catenin; endocytosis; catenin signaling ... See more keywords