Appendiceal sessile serrated lesions are distinct from their right-sided colonic counterparts and may be precursors for appendiceal mucinous neoplasms.
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DOI: 10.1016/j.humpath.2022.01.008
Abstract: Low-grade appendiceal mucinous neoplasms (LAMNs) can occur concurrently with appendiceal sessile serrated lesions (SSLs). To interrogate relatedness, we performed multigene and immunohistochemical characterizations of paired and unpaired SSLs and LAMNs. We evaluated 62 serrated lesions… read more here.
Keywords: lamns; appendiceal mucinous; serrated lesions; sessile serrated ... See more keywords
Acetic acid for subtle serrated lesions of the right colon: does it facilitate diagnosis?
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DOI: 10.1055/a-1158-8780
Abstract: Sessile serrated adenomas/polyps (SSA/ Ps) have a well-established malignant potential. Because of their subtle appearance, they pose a special diagnostic challenge for the endoscopist [1, 2]. Improving SSA/P detection and characterization during routine colonoscopy is… read more here.
Keywords: right colon; serrated lesions; acetic acid; acid ... See more keywords
Implementation of an e‐learning module improves consistency in the histopathological diagnosis of sessile serrated lesions within a nationwide population screening programme
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DOI: 10.1111/his.13155
Abstract: Distinguishing premalignant sessile serrated lesions (SSLs) from hyperplastic polyps (HPs) is difficult for pathologists in daily practice. We aimed to evaluate nationwide variability within histopathology laboratories in the frequency of diagnosing an SSL as compared… read more here.
Keywords: histopathology; learning module; sessile serrated; screening programme ... See more keywords
Local recurrence after endoscopic resection of sessile serrated lesions: A multicenter prospective study by the Osaka Gut Forum
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DOI: 10.1111/jgh.16032
Abstract: Sessile serrated lesions (SSLs) act as precursors to colorectal cancer, sometimes harbor carcinomas, and are sometimes incompletely resected. We aimed to evaluate local recurrence after endoscopic resection of SSL ≥10 mm. read more here.
Keywords: serrated lesions; endoscopic resection; local recurrence; recurrence endoscopic ... See more keywords
Risk factors for sessile serrated lesions among Chinese patients undergoing colonoscopy.
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DOI: 10.1111/jgh.16200
Abstract: BACKGROUND AND AIM Serrated polyps have been recognized as a premalignant lesion accounting for a significant proportion of colorectal cancer. Limited data are available regarding the risk factors for colorectal sessile serrated lesions (SSLs). We… read more here.
Keywords: serrated lesions; factors sessile; risk factors; risk ... See more keywords
A Retrospective Analysis of Colorectal Serrated Lesions from 2005 to 2014 in a Single Center: Importance of the Establishment of Diagnostic Patterns
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DOI: 10.1155/2018/5946057
Abstract: Background Serrated colorectal lesions are increasingly recognized as an important process in the development of colorectal cancer. Endoscopic and histological diagnosis may be difficult, and knowledge of the serrated lesions is important for the establishment… read more here.
Keywords: single center; 2005 2014; serrated adenomas; retrospective analysis ... See more keywords
Serrated Lesions of the Colon-Rectum: A Focus on New Diagnostic Tools and Current Management
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DOI: 10.1155/2019/9179718
Abstract: Prompt diagnosis and correct management of the so called “serrated lesions” (SLs) of the colon-rectum are generally considered of crucial importance in the past years, mainly due to their histological heterogeneity and peculiar clinical and… read more here.
Keywords: management; serrated lesions; sls; colon rectum ... See more keywords
Exome sequencing characterizes the somatic mutation spectrum of early serrated lesions in a patient with serrated polyposis syndrome (SPS)
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DOI: 10.1186/s13053-017-0082-9
Abstract: BackgroundSerrated or Hyperplastic Polyposis Syndrome (SPS, HPS) is a yet poorly defined colorectal cancer (CRC) predisposition characterised by the occurrence of multiple and/or large serrated polyps throughout the colon. A serrated polyp-CRC sequence (serrated pathway)… read more here.
Keywords: exome sequencing; syndrome sps; polyposis syndrome; early serrated ... See more keywords
Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions
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DOI: 10.1371/journal.pone.0258878
Abstract: Background Adenomas and serrated lesions represent heterogeneous sets of early precursors in the colorectum with varying malignant potential. They are often distinguished by their histopathologic differences, but little is known about potential differences in regulation… read more here.
Keywords: apoptosis; proliferation apoptosis; adenomas serrated; expression ... See more keywords
Increased GS-II lectin binding and SATB2 downregulation are biological features for sessile serrated lesions and microvesicular hyperplastic polyps.
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DOI: 10.2139/ssrn.4272534
Abstract: Sessile serrated lesions (SSLs) and microvesicular hyperplastic polyps (MVHPs) are colorectal lesions displaying gastric differentiation. Griffonia simplicifolia-II (GS-II) is a lectin specific to terminal α/βGlcNAc residues. Here, we assessed GS-II binding and performed immunostaining for… read more here.
Keywords: serrated lesions; ssls mvhps; sessile serrated; hyperplastic polyps ... See more keywords
Significance of the Entire Appendiceal Evaluation in the Diagnosis of Serrated Lesions, Low-Grade Appendiceal Mucinous Neoplasm, and Appendiceal Diverticulosis Disease
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DOI: 10.3389/fonc.2021.812794
Abstract: Objective This study was conducted in order to investigate the significance of the entire appendiceal evaluation in the pathological diagnosis of appendiceal serrated lesions, low-grade appendiceal mucinous neoplasm (LAMN), and appendiceal diverticulosis disease (ADD). Methods… read more here.
Keywords: appendiceal evaluation; significance entire; serrated lesions; appendiceal serrated ... See more keywords