Effect of resveratrol on Sertoli cell proliferation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27350
Abstract: Resveratrol (RSV), a polyphenolic compound largely found in red grape skin, has been used as a nutritional supplement as it exhibits beneficial health effects, such as anticancer, cardioprotective, antiaging, and anti‐inflammatory. Particularly, it has been… read more here.
Keywords: cell proliferation; sertoli; sertoli cell; rsv ... See more keywords
Sertoli cell adaptation to glucose deprivation: Potential role of AMPK in the regulation of lipid metabolism
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.30399
Abstract: Sertoli cells (SCs) provide an adequate environment for germ cell development. SCs possess unique features that meet germ cells' metabolic demands: they produce lactate from glucose, which is delivered as energy substrate to germ cells.… read more here.
Keywords: cell; sertoli; glucose deprivation; lipid metabolism ... See more keywords
Establishment of a pure culture of immature Sertoli cells by PDGFRA staining and cell sorting
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23574
Abstract: Sertoli cells are key somatic cells in the testis that form seminiferous tubules and support spermatogenesis. The isolation of pure Sertoli cells is important for their study. However, it is a difficult effort because of… read more here.
Keywords: sertoli; cell; establishment pure; cell sorting ... See more keywords
Sertoli Cell Preparation for Co-immunoprecipitation.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7698-0_6
Abstract: Most techniques to study protein-protein interactions, gene expression or signal transduction, among others, in Sertoli cells, depend on obtaining a protein extract of such cells. This is accomplished by lysing the Sertoli cells and solubilizing… read more here.
Keywords: sertoli cell; sertoli; sertoli cells; preparation immunoprecipitation ... See more keywords
Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
Sign Up to like & getrecommendations! Published in 2017 at "Cell Discovery"
DOI: 10.1038/celldisc.2017.13
Abstract: Sertoli cells have dual roles during the cells’ lifetime. In the juvenile mammal, Sertoli cells proliferate and create the structure of the testis, and during puberty they cease to proliferate and take on the adult… read more here.
Keywords: sertoli cell; sertoli; sertoli cells; rat sertoli ... See more keywords
Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41051-1
Abstract: The elevated level of Steroidogenic Factor 1 (Nr5a1, Sf-1) expression in the male gonadal development pathway, post sex determination, implies a vital role in testis gonadal differentiation. In this study we generated Sertoli cell-specific Nr5a1… read more here.
Keywords: sertoli cell; sertoli; sex determination; post sex ... See more keywords
Regulation of STUB1 expression and its biological significance in mouse Sertoli cells
Sign Up to like & getrecommendations! Published in 2022 at "Systems Biology in Reproductive Medicine"
DOI: 10.1080/19396368.2022.2027554
Abstract: Abstract STIP1 Homology and U-Box Containing Protein 1 (STUB1), a ubiquitin E3 ligase initially involved in immune responses, has recently emerged as a pleiotropic regulator of different biological systems, including skeletal and male reproduction systems.… read more here.
Keywords: sertoli; stub1 expression; expression; testis ... See more keywords
Androgen Indirectly Regulates Gap Junction Component Connexin 43 via Wilms Tumor-1 in Sertoli Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Stem cells and development"
DOI: 10.1089/scd.2019.0166
Abstract: In mammals, spermatogenesis is closely related to intercellular interactions of germ cells and surrounding Sertoli cells, i.e. blood-testis barrier (BTB) and gap junction, which are subjected to hormone signals in testicular seminiferous tubules. Androgen signal… read more here.
Keywords: sertoli; sertoli cells; gap junction; androgen indirectly ... See more keywords
Sertoli cells require TDP-43 to support spermatogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac165
Abstract: Abstract TAR DNA binding protein of 43 kD (TDP-43) is an evolutionarily conserved, ubiquitously expressed transcription factor and RNA-binding protein with major human health relevance. TDP-43 is present in Sertoli and germ cells of the… read more here.
Keywords: spermatogenesis; sertoli; germ; cells require ... See more keywords
MicroRNA-125a-5p modulates the proliferation and apoptosis of TM4 Sertoli cells by targeting RAB3D and regulating the PI3K/AKT signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular human reproduction"
DOI: 10.1093/molehr/gaab049
Abstract: Sertoli cells are cells that provide protection and nutrition for developing sperm. Each stage of sperm development occurs on the surface of Sertoli cells. MicroRNA (MiR)-125a-5p is involved in male reproduction. The current research aimed… read more here.
Keywords: apoptosis; sertoli cell; sertoli; rab3d ... See more keywords
The PI3K/AKT signaling pathway: How does it regulate development of Sertoli cells and spermatogenic cells?
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-457
Abstract: The PI3K/AKT signaling pathway is one of the most crucial regulatory mechanisms in animal cells, which can mainly regulate proliferation, survival and anti-apoptosis in cell lines. In the seminiferous epithelium, most studies were concentrated on… read more here.
Keywords: sertoli; pi3k akt; signaling pathway; cells spermatogenic ... See more keywords