Hepatocytes cocultured with Sertoli cells in bioreactor favors Sertoli barrier tightness in rat
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3360
Abstract: The lack of a reliable in vitro system to assess reprotoxicity is an emerging problem in the context of European law for Registration, Evaluation, Authorization and Restriction of Chemicals (REACH, 2007), as it requires a… read more here.
Keywords: bioreactor favors; cells bioreactor; sertoli barrier; sertoli cells ... See more keywords
Wnt/β‐catenin signaling enhances transcription of the CX43 gene in murine Sertoli cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27973
Abstract: Sertoli cells provide the nutritional and metabolic support for germ cells. Wnt/β‐catenin signaling is important for the development of the seminiferous epithelium during embryonic age, although after birth this pathway is downregulated. Cx43 gene codes… read more here.
Keywords: cx43 gene; sertoli cells; catenin; wnt catenin ... See more keywords
Three‐dimensional electrospun gelatin scaffold coseeded with embryonic stem cells and sertoli cells: A promising substrate for in vitro coculture system
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28517
Abstract: In this study, we present an electrospun gelatin (EG) scaffold to mimic the extracellular matrix of the testis. The EG scaffold was synthesized by electrospinning and crosslinked with glutaraldehyde vapor to decrease its water solubility… read more here.
Keywords: sertoli cells; stem cells; electrospun gelatin; coculture ... See more keywords
Comparative analysis of porcine iPSCs derived from Sertoli cells and fibroblasts
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30903
Abstract: Porcine embryonic fibroblasts (PEFs) can be directly reprogrammed into porcine induced pluripotent stem cells (piPSCs). However, the reprogramming process is generally lengthy and inefficient. Here, we established a fast and efficient induction system of piPSCs… read more here.
Keywords: comparative analysis; cell; porcine ipscs; porcine ... See more keywords
MiR‐8‐3p regulates hyperthermia‐induced lactate secretion by targeting PPP2R5B in boar Sertoli cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23265
Abstract: Lactate produced by glycolysis in Sertoli cells (SCs) is the main energy substrate for developing germ cells and plays a vital role in spermatogenesis. MicroRNAs (miRNAs) function as posttranscriptional regulators of gene expression in biological… read more here.
Keywords: hyperthermia; secretion targeting; boar; lactate secretion ... See more keywords
Establishment of a pure culture of immature Sertoli cells by PDGFRA staining and cell sorting
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23574
Abstract: Sertoli cells are key somatic cells in the testis that form seminiferous tubules and support spermatogenesis. The isolation of pure Sertoli cells is important for their study. However, it is a difficult effort because of… read more here.
Keywords: sertoli; cell; establishment pure; cell sorting ... See more keywords
Dysregulated genes in undifferentiated spermatogonia and Sertoli cells are associated with the spermatogenic arrest in cattleyak
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23653
Abstract: Hybrid male sterility (HMS) is a reproductive isolation mechanism limiting the formation of fertile offspring through interspecific fertilization. Cattleyak is the interspecific hybrid presenting significant heterosis in several economic traits, but HMS restricted its wide… read more here.
Keywords: undifferentiated spermatogonia; cattleyak; dysregulated genes; spermatogonia sertoli ... See more keywords
The transcription factors Junb and Fosl2 cooperate to regulate Cdh3 expression in 15P‐1 Sertoli cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23656
Abstract: In Sertoli cells of the testis, cadherins (Cdh) are important cell‐to‐cell interaction proteins and contribute to the formation of the blood‐testis barrier being essential for germ cells' protection. P‐cadherin or Cdh3 is only expressed in… read more here.
Keywords: cdh3; junb fosl2; 15p sertoli; transcription factors ... See more keywords
Co‐culturing or conditioned medium of Sertoli cells: Which one supports in vitro maturation of bovine oocytes and developmental competency of resulting embryos?
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.939
Abstract: Abstract Background Sertoli cells (SCs) as supportive cells in the seminiferous tubule play an essential role in the nutrition and development of adjacent cells by secreting several beneficial growth factors, stimulators and cytokines which can… read more here.
Keywords: culture; maturation; group; conditioned medium ... See more keywords
Proteome Profiling of Sertoli Cells Using a GeLC-MS/MS Strategy.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7698-0_13
Abstract: Proteomics is a technology that allows to decipher the molecular networks involved in the regulation of biological processes such as spermatogenesis. Sertoli cells (SCs) are key players in the paracrine control of this process. Envisioning… read more here.
Keywords: gelc strategy; profiling sertoli; cells using; sertoli cells ... See more keywords
Sertoli Cell Preparation for Co-immunoprecipitation.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7698-0_6
Abstract: Most techniques to study protein-protein interactions, gene expression or signal transduction, among others, in Sertoli cells, depend on obtaining a protein extract of such cells. This is accomplished by lysing the Sertoli cells and solubilizing… read more here.
Keywords: sertoli cell; sertoli; sertoli cells; preparation immunoprecipitation ... See more keywords