Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals
Sign Up to like & getrecommendations! Published in 2021 at "Genetic Epidemiology"
DOI: 10.1002/gepi.22392
Abstract: Serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are biomarkers for liver health. Here we report the largest genome‐wide association analysis to date of serum ALT and AST levels in over 388k people of European… read more here.
Keywords: genome wide; alt ast; serum alanine; serum ... See more keywords
Serum Alanine Aminotransferase Elevations in Survivors of Childhood Cancer: A Report From the St. Jude Lifetime Cohort Study
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30176
Abstract: The purpose of this study was to define the prevalence of and risk factors for elevated serum alanine aminotransferase (ALT) level among adult childhood cancer survivors (CCS). The study cohort comprised 2,751 CCS from the… read more here.
Keywords: serum alanine; jude lifetime; alanine aminotransferase; study ... See more keywords
THE RELATIONSHIP OF SERUM ALANINE AMINOTRANSFERASE TO ARTERIAL STIFFNESS IN YOUNG HEALTHY ADULTS
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000572132.28665.2e
Abstract: Objective:Increased arterial stiffness (AS), measured as increased pulse wave velocity (PWV), central blood pressure (BPao) has been considered as important aspect of vascular aging and independent risk factor for both cardiovascular events and overall mortality.… read more here.
Keywords: serum alanine; arterial stiffness; alanine aminotransferase; stiffness ... See more keywords
Combined effect of serum alanine aminotransferase and gamma-glutamyltransferase on incidence of diabetes mellitus
Sign Up to like & getrecommendations! Published in 2020 at "Medicine"
DOI: 10.1097/md.0000000000018963
Abstract: Abstract High levels of serum alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) are associated with increased diabetes risk. In the present study, we investigated the combined effects of ALT and GGT on the development of diabetes… read more here.
Keywords: alanine aminotransferase; alt ggt; development diabetes; serum alanine ... See more keywords
Genetic variants associated with serum alanine aminotransferase levels among patients with hepatitis C virus infection: A genome‐wide association study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13550
Abstract: Information on genetic variants associated with elevated serum alanine aminotransferase (ALT) levels remains limited. A genome‐wide association study was performed to identify single‐nucleotide polymorphisms (SNPs) associated with ALT levels. The ALT‐associated SNP was further evaluated… read more here.
Keywords: genome wide; serum alanine; genetic variants; alt levels ... See more keywords
Visceral fat is associated with elevation of serum alanine aminotransferase and gamma glutamyltransferase in middle-aged Chinese adults
Sign Up to like & getrecommendations! Published in 2018 at "Postgraduate Medical Journal"
DOI: 10.1136/postgradmedj-2018-135644
Abstract: Background Elevation of hepatic enzymes is associated with insulin resistance, dyslipidaemia and obesity. However, the factors behind elevation of liver enzymes remain unclear. The aim of this study was to compare the role of abdominal… read more here.
Keywords: vat sat; serum alanine; alanine aminotransferase; ggt ... See more keywords