Interactions of zearalenone and its reduced metabolites α-zearalenol and β-zearalenol with serum albumins: species differences, binding sites, and thermodynamics
Sign Up to like & getrecommendations! Published in 2018 at "Mycotoxin Research"
DOI: 10.1007/s12550-018-0321-6
Abstract: Zearalenone (ZEN) is a mycotoxin produced by Fusarium species. ZEN mainly appears in cereals and related foodstuffs, causing reproductive disorders in animals, due to its xenoestrogenic effects. The main reduced metabolites of ZEN are α-zearalenol… read more here.
Keywords: thermodynamics; zel; reduced metabolites; affinity ... See more keywords
Investigating the interaction of juglone (5-hydroxy-1, 4-naphthoquinone) with serum albumins using spectroscopic and in silico methods
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1094-0
Abstract: The interaction between juglone at the concentration range of 10–110 µM and bovine serum albumin (BSA) or human serum albumin (HSA) at the constant concentration of 11 µM was investigated by fluorescence and UV absorption spectroscopy under… read more here.
Keywords: interaction; juglone; albumin; interaction juglone ... See more keywords
Squaraine dyes as serum albumins probes: Synthesis, photophysical experiments and molecular docking studies.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105221
Abstract: Three barbiturate squaraine dyes derived from indolenine or benzothiazole, with different barbituric acid derivatives were prepared, characterized and photophysically evaluated by standard spectroscopic methods. As expectable for squaraines, these dyes showed narrow and intense absorption… read more here.
Keywords: albumins probes; docking studies; dyes serum; squaraine dyes ... See more keywords
Interactions of perfluorooctanoic acid and perfluorooctanesulfonic acid with serum albumins by native mass spectrometry, fluorescence and molecular docking.
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2018.01.152
Abstract: The binding information of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) with bovine and human serum albumins was investigated and characterized in details by using a combination method of electrospray ionization mass spectrometry (ESI-MS), fluorescence,… read more here.
Keywords: pfoa pfos; serum; acid; serum albumins ... See more keywords
How does cholinium cation surpass tetraethylammonium cation in amino acid-based ionic liquids for thermal and structural stability of serum albumins?
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.01.135
Abstract: In this study, we report how similarly two serum albumins (bovine serum albumin (BSA) and human serum albumin (HSA)) respond in the presence of different concentration of aromatic amino acid based ionic liquids (AAILs), which… read more here.
Keywords: cation; acid based; amino acid; stability ... See more keywords
Multifunctional supramolecular ionic metallosurfactants (SMIMSs) for antimicrobial, anticancer and serum albumins binding
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.04.138
Abstract: Abstract Towards the development of metallodrugs such as metallosurfactants, it is very significant to know about their hydrophobicity, micellization and biological activities. Here, the in vitro biological studies of supramolecular ionic metallosurfactants (SMIMSs) namely MOTA,… read more here.
Keywords: antimicrobial anticancer; ionic metallosurfactants; anticancer serum; metallosurfactants smimss ... See more keywords
Exploring the interactions of a DNA aptamer with human serum albumins: simulation studies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1224733
Abstract: The level of blood glucose is a traditional indicator for diabetes diagnosis and treatment. To track diabetes progression, the levels of blood sugar and the percentage of glycated hemoglobin (HbA1c... read more here.
Keywords: aptamer human; human serum; exploring interactions; dna aptamer ... See more keywords
An Investigation on intermolecular interaction between Bis(indolyl)methane and HSA and BSA using multi technique methods
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1264890
Abstract: Bis(indolyl)methane (BIM) as one of the main active components of anticancer and antibacterial drugs is applied in medicinal and extensive area of chemistry. In this research, interaction of human and bovine serum albumins as drug… read more here.
Keywords: human bovine; serum; spectroscopy; bovine serum ... See more keywords
Far-red pentamethine cyanine dyes as fluorescent probes for the detection of serum albumins
Sign Up to like & getrecommendations! Published in 2020 at "Royal Society Open Science"
DOI: 10.1098/rsos.200453
Abstract: Benzothiazole based cyanine dyes with bridged groups in the pentamethine chain were studied as potential far-red fluorescent probes for protein detection. Spectral-luminescent properties were characterized for unbound dyes and in the presence of serum albumins… read more here.
Keywords: detection; pentamethine cyanine; cyanine dyes; far red ... See more keywords
Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins
Sign Up to like & getrecommendations! Published in 2018 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.117.078782
Abstract: N-{4-Chloro-2-[(1-oxidopyridin-4-yl)carbonyl]phenyl}-4-(propan-2-yloxy)benzenesulfonamide (MLN3126) is an orally available chemokine C-C motif receptor 9 selective antagonist. In nonclinical pharmacokinetic studies of MLN3126, nonextractable radioactivity was observed in plasma after oral administration of 14C-labeled MLN3126 ([14C]MLN3126) to Sprague-Dawley (SD)… read more here.
Keywords: chemokine motif; covalent binding; mln3126; covalent ... See more keywords
Testing Serum Albumins and Cyclodextrins as Potential Binders of the Mycotoxin Metabolites Alternariol-3-Sulfate, Alternariol-9-Monomethylether and Alternariol-9-Monomethylether-3-Sulfate
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214353
Abstract: Alternaria mycotoxins, including alternariol (AOH), alternariol-9-monomethylether (AME), and their masked/modified derivatives (e.g., sulfates or glycosides), are common food contaminants. Their acute toxicity is relatively low, while chronic exposure can lead to the development of adverse… read more here.
Keywords: albumins cyclodextrins; alternariol; serum albumins; sulfate ... See more keywords