Serum alpha-mannosidase as an additional barrier to eliciting oligomannose-specific HIV-1-neutralizing antibodies
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DOI: 10.1038/s41598-020-64500-8
Abstract: Oligomannose-type glycans on HIV-1 gp120 form a patch that is targeted by several broadly neutralizing antibodies (bnAbs) and that therefore is of interest to vaccine design. However, attempts to elicit similar oligomannose-specific bnAbs by immunizing… read more here.
Keywords: eliciting oligomannose; oligomannose specific; mannosidase trimming; mannosidase ... See more keywords
Unsuspected primary malignancy in the setting of elevated serum alpha-fetoprotein
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DOI: 10.1080/08998280.2019.1582941
Abstract: Abstract Hepatocellular carcinoma is the most common solid liver cancer and is screened for with serum alpha-fetoprotein (AFP) in patients with chronic hepatitis or cirrhosis. However, other tumors can produce AFP, and one of these… read more here.
Keywords: primary malignancy; alpha fetoprotein; unsuspected primary; serum alpha ... See more keywords
High serum alpha‐fetoprotein levels in primary infertile men
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DOI: 10.1111/andr.13297
Abstract: Alfa‐fetoprotein (AFP) is a serum glycoprotein highly produced during fetal development. While AFP synthesis drops dramatically after birth, AFP production only persists or returns under specific pathological condition. read more here.
Keywords: fetoprotein levels; fetoprotein; levels primary; high serum ... See more keywords
Investigation on urinary and serum alpha klotho in dogs with chronic kidney disease
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DOI: 10.1186/s12917-020-02458-5
Abstract: Background As a co-receptor for fibroblast growth factor 23, klotho plays a pivotal role in phosphate metabolism. The kidney is known to be the main source of soluble alpha-klotho and the principal regulator of its… read more here.
Keywords: alpha klotho; klotho; concentration; serum alpha ... See more keywords