Systems pharmacology modeling of drug‐induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pharmacology and Therapeutics"
DOI: 10.1002/cpt.619
Abstract: Elevations in serum bilirubin during drug treatment may indicate global liver dysfunction and a high risk of liver failure. However, drugs also can increase serum bilirubin in the absence of hepatic injury by inhibiting specific… read more here.
Keywords: inhibition; hyperbilirubinemia; drug; pharmacology ... See more keywords
Clinical significance of serum bilirubin in primary Sjögren syndrome patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23090
Abstract: The purpose of our research was to demonstrate the clinical significance of serum bilirubin in primary Sjögren syndrome patients (pSS). read more here.
Keywords: gren syndrome; bilirubin primary; significance serum; primary gren ... See more keywords
Serum bilirubin is associated with a reduced risk of subsequent recurrent wheezing following acute respiratory syncytial virus bronchiolitis.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatric pulmonology"
DOI: 10.1002/ppul.26493
Abstract: BACKGROUND Bilirubin is a potent antioxidant and anti-inflammatory molecule that has been shown to ameliorate airway inflammation. We aimed to study whether serum bilirubin is protective and can predict the development of subsequent recurrent wheezing… read more here.
Keywords: bilirubin; subsequent recurrent; serum bilirubin; recurrent wheezing ... See more keywords
Total serum bilirubin levels and sensorineural hearing loss in the US adolescents: NHANES 2007-2010.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pediatric otorhinolaryngology"
DOI: 10.1016/j.ijporl.2017.12.001
Abstract: OBJECTIVE We aimed to investigate whether current levels of total serum bilirubin are associated with different subtypes of sensorineural hearing loss (SNHL) in adolescents. METHODS A set of cross-sectional data from the National Health and… read more here.
Keywords: one ear; hearing loss; least one; total serum ... See more keywords
Serum Bilirubin Associated with Stroke Severity and Prognosis: Preliminary Findings on Liver Function after Acute Ischemic Stroke
Sign Up to like & getrecommendations! Published in 2022 at "Neurological Research"
DOI: 10.1080/01616412.2022.2119724
Abstract: ABSTRACT Objective This study investigates relationships between serum bilirubin, stroke severity, and prognosis of patients with acute ischemic stroke (AIS) to elucidate the roles of the liver in AIS. Methods This retrospective study collected data… read more here.
Keywords: stroke; serum bilirubin; prognosis; stroke severity ... See more keywords
Relationship between anemia, serum bilirubin concentrations, and diabetic retinopathy in individuals with type 2 diabetes
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000017693
Abstract: Abstract This study sought to assess the hypothesis that anemia is associated with diabetic retinopathy in type 2 diabetes mellitus (DM) and investigate the factors mediating the relationship between anemia and diabetic retinopathy. In total,… read more here.
Keywords: anemia; individuals type; serum bilirubin; diabetic retinopathy ... See more keywords
Antioxidant status of serum bilirubin, uric acid and albumin in pemphigus vulgaris
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.13289
Abstract: Oxidative stress and low antioxidant status are implicated in the pathogenesis of inflammatory and autoimmune diseases. Pemphigus vulgaris (PV) is an extremely severe autoimmune bullous dermatosis characterized by intraepithelial bullae on the skin and mucosa,… read more here.
Keywords: status; pemphigus vulgaris; status serum; serum bilirubin ... See more keywords
Quality improvement initiative using transcutaneous bilirubin nomogram to decrease serum bilirubin sampling in low-risk babies
Sign Up to like & getrecommendations! Published in 2019 at "BMJ Paediatrics Open"
DOI: 10.1136/bmjpo-2018-000403
Abstract: Background Screening for neonatal hyperbilirubinaemia in the postnatal ward has traditionally been performed using serum bilirubin sampling, but this has significant drawbacks such as risk of infection and slower reporting time. Objective We aimed to… read more here.
Keywords: bilirubin sampling; bilirubin; serum bilirubin; implementation phase ... See more keywords
Jaundice as a diagnostic and therapeutic problem-General practitioner's approach.
Sign Up to like & getrecommendations! Published in 2021 at "Digestive diseases"
DOI: 10.1159/000517301
Abstract: Background: Jaundice is a common clinical finding in clinical practice of hepatologists and general practitioners. It occurs when serum bilirubin levels exceed 3 mg/dL. Summary: In this review, we summarize the pathophysiological mechanism of jaundice,… read more here.
Keywords: serum bilirubin; patient jaundice; approach; jaundice ... See more keywords
Serum Bilirubin Levels and the Presence and Progression of Abdominal Aortic Aneurysms
Sign Up to like & getrecommendations! Published in 2017 at "Angiology"
DOI: 10.1177/0003319716660240
Abstract: The relationship between bilirubin levels and peripheral artery disease has been documented. Our aim was to demonstrate the possible relationship between serum bilirubin levels and abdominal aortic aneurysms (AAAs). The study included 219 patients, 110… read more here.
Keywords: presence; aortic aneurysms; bilirubin; bilirubin levels ... See more keywords
A Prospective Comparison of Transcutaneous and Serum Bilirubin Within Brief Time Intervals
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Pediatrics"
DOI: 10.1177/0009922817701170
Abstract: The American Academy of Pediatrics recommends screening newborns ≥35 weeks’ gestation with total serum bilirubin (TSB) or transcutaneous bilirubin (TcB) to detect hyperbilirubinemia. Retrospective studies show TcB measurements strongly correlate with TSB; however, few prospective… read more here.
Keywords: tsb; bilirubin; tcb; serum bilirubin ... See more keywords