Overexpression of GRP78 enhances survival of CHO cells in response to serum deprivation and oxidative stress
Sign Up to like & getrecommendations! Published in 2017 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.201500152
Abstract: Chinese hamster ovary (CHO) cells are regarded as one of the most commonly used mammalian hosts, which decreases the productivity due to loss in culture viability. Overexpressing antiapoptosis genes in CHO cells was developed as… read more here.
Keywords: cho cells; cells response; serum deprivation; cho ... See more keywords
Serum deprivation limits loss and promotes recovery of tenogenic phenotype in tendon cell culture systems
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.24761
Abstract: Current knowledge gaps on tendon tissue healing can partly be ascribed to the limited availability of physiologically relevant culture models. An unnatural extracellular matrix, high serum levels and random cell morphology in vitro mimic strong… read more here.
Keywords: phenotype; serum; tendon; serum deprivation ... See more keywords
Morphine stimulates angiogenesis through Akt/mTOR/eIF4E activation under serum deprivation or H2O2‐induced oxidative stress condition
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13191
Abstract: Morphine is an opioid analgesic drug routinely used to treat pain in several medical conditions including cancer. Increasing evidence has shown that morphine can directly modulate cancer growth via regulating angiogenesis. In this work, we… read more here.
Keywords: deprivation h2o2; angiogenesis; morphine; h2o2 induced ... See more keywords
Serum deprivation‐response protein regulates aldehyde dehydrogenase 1 through integrin‐linked kinase signaling in endometrioid carcinoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.14007
Abstract: Endometrioid carcinoma (EC) is one of the most common malignancies of the female genital system. We reported previously that aldehyde dehydrogenase 1 (ALDH1), a predominant isoform of the ALDH family in mammals and a potential… read more here.
Keywords: response protein; endometrioid carcinoma; deprivation response; integrin linked ... See more keywords
Melatonin protects hippocampal HT22 cells from the effects of serum deprivation specifically targeting mitochondria
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DOI: 10.1371/journal.pone.0203001
Abstract: Neurons contain a high number of mitochondria, these neuronal cells produce elevated levels of oxidative stress and live for a long time without proliferation; therefore, mitochondrial homeostasis is crucial to their health. Investigations have recently… read more here.
Keywords: ht22; hippocampal ht22; melatonin protects; protects hippocampal ... See more keywords
A systematic analysis reveals gene expression alteration of serum deprivation response (SDPR) gene is significantly associated with the survival of patients with cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology reports"
DOI: 10.3892/or.2019.7212
Abstract: Serum deprivation response (SDPR) gene has been recently characterized as a gene signature marker or serving a tumor suppressor role in specific types of cancer. However, gene expression alterations of SDPR in various types of… read more here.
Keywords: deprivation response; serum deprivation; sdpr; expression ... See more keywords