Articles with "serum derived" as a keyword



Serum‐derived bovine immunoglobulin treatment in COVID‐19 is associated with faster resolution of symptoms: A randomized pilot clinical trial

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Published in 2024 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70005

Abstract: Effective treatment to prevent hospitalization and death in people with COVID‐19 exists, but people still need interventions that alleviate symptoms without drug interactions. Oral serum‐derived bovine immunoglobulins (SBI) may reduce symptoms and time‐to‐improvement in people… read more here.

Keywords: covid; derived bovine; mild moderate; moderate covid ... See more keywords

Efficient Delivery of Tyrosinase Related Protein-2 (TRP2) Peptides to Lymph Nodes using Serum-Derived Exosomes.

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Published in 2018 at "Macromolecular bioscience"

DOI: 10.1002/mabi.201800301

Abstract: Exosomes (EXO) are considered to be versatile carriers for biomolecules; however, the delivery of therapeutic peptides using EXOs poses several challenges. In this study, the efficiency of serum-derived EXOs in delivering tyrosinase-related protein-2 (TRP2) peptides… read more here.

Keywords: trp2; serum derived; lymph nodes; peptides lymph ... See more keywords

Proteomic Profiling of Serum-Derived Extracellular Vesicles in Diffuse Idiopathic Skeletal Hyperostosis Patients.

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Published in 2025 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.4c01015

Abstract: This study focuses on the proteomic profiles of serum-derived EVs in diffuse idiopathic skeletal hyperostosis (DISH), aiming to identify the potential diagnostic biomarkers for DISH. Serum-EVs were separated using a differential centrifugation technique. Then, label-free-liquid… read more here.

Keywords: serum; diffuse idiopathic; evs ahsg; serum evs ... See more keywords

Exosomal TAR DNA binding protein 43 profile in canine model of amyotrophic lateral sclerosis: a preliminary study in developing blood-based biomarker for neurodegenerative diseases

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Published in 2022 at "Annals of Medicine"

DOI: 10.1080/07853890.2022.2153162

Abstract: Objective Blood-based biomarkers provide a crucial information in progress of neurodegenerative diseases with minimally invasive sampling method. Validated blood-based biomarker application in people with amyotrophic lateral sclerosis would derive numerous benefits. Canine degenerative myelopathy is… read more here.

Keywords: biomarker; serum derived; lateral sclerosis; blood based ... See more keywords

Serum-Derived Hyaluronan-Associated Protein Is a Novel Biomarker for Inflammatory Bowel Diseases

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Published in 2017 at "Digestion"

DOI: 10.1159/000456071

Abstract: Background/Aims: We evaluated the role of serum-derived hyaluronan-associated protein (SHAP) in inflammatory bowel disease (IBD) pathogenesis and its potential as a novel IBD biomarker. Methods: We studied the SHAP expression in a mouse model of… read more here.

Keywords: associated protein; derived hyaluronan; serum derived; biomarker ... See more keywords

Clinical and Pathologic Remission of Pediatric Ulcerative Colitis with Serum-Derived Bovine Immunoglobulin Added to the Standard Treatment Regimen

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Published in 2017 at "Case Reports in Gastroenterology"

DOI: 10.1159/000475923

Abstract: Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is particularly troublesome for pediatric patients, as current therapeutic options consist of biologic agents and steroids which alter the immune response and have the harmful… read more here.

Keywords: serum derived; ulcerative colitis; treatment regimen; derived bovine ... See more keywords

Serum-derived exosomes from neurofibromatosis type 1 congenital tibial pseudarthrosis impaired bone by promoting osteoclastogenesis and inhibiting osteogenesis

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Published in 2020 at "Experimental Biology and Medicine"

DOI: 10.1177/1535370220962737

Abstract: Treatment of congenital pseudarthrosis of the tibia (CPT) still is full of challenges in pediatric orthopedist. Serum-derived exosomes (SDEs) have been proven to be participated in bone remodeling. However, the molecular changes in SDEs of… read more here.

Keywords: serum derived; bone; neurofibromatosis type; pseudarthrosis ... See more keywords

Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery

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Published in 2022 at "Experimental Biology and Medicine"

DOI: 10.1177/15353702221092984

Abstract: The spread of SARS-CoV-2 over the entire world is more commonly known as COVID-19. COVID-19 has impacted society in every aspect of routine life. SARS-CoV-2 infection is often misdiagnosed as influenza or seasonal upper respiratory… read more here.

Keywords: diagnostic tool; convalescent serum; mrna delivery; serum derived ... See more keywords

Elevated serum extracellular vesicle arginase 1 in type 2 diabetes mellitus: a cross-sectional study in middle-aged and elderly population

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Published in 2022 at "BMC Endocrine Disorders"

DOI: 10.1186/s12902-022-00982-z

Abstract: Background Serum extracellular vesicle (EV)-derived arginase 1 (ARG 1) plays a critical role in diabetes-associated endothelial dysfunction. This study was performed to determine the levels of serum EV-derived ARG 1 in T2DM and non-T2DM participants… read more here.

Keywords: study; derived arg; serum derived; t2dm ... See more keywords

Potential mechanisms of effects of serum‐derived bovine immunoglobulin/protein isolate therapy in patients with diarrhea‐predominant irritable bowel syndrome

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Published in 2017 at "Physiological Reports"

DOI: 10.14814/phy2.13170

Abstract: Serum‐derived bovine immunoglobulin/protein isolate (SBI), an oral nutritional therapy, is efficacious in diverse diarrheal diseases. In an open‐label study in 15 patients with irritable bowel syndrome‐diarrhea (IBS‐D), we evaluated effects of SBI (5.0 g, twice… read more here.

Keywords: serum derived; bowel; immunoglobulin protein; therapy ... See more keywords

Serum Derived Exosomes From Pancreatic Cancer Patients Promoted Metastasis: An iTRAQ-Based Proteomic Analysis

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Published in 2019 at "OncoTargets and therapy"

DOI: 10.2147/ott.s229494

Abstract: Background Pancreatic cancer (PC) is one of the most aggressive malignancies and has a poor prognosis despite being extensively researched. The role of serum-derived exosomes in tumorigenesis and the development of PC is still unclear.… read more here.

Keywords: itraq based; serum derived; derived exosomes; pancreatic cancer ... See more keywords