Aging-Related Changes in Cognition and Cortical Integrity are Associated With Serum Expression of Candidate MicroRNAs for Alzheimer Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Cerebral cortex"
DOI: 10.1093/cercor/bhy323
Abstract: Evidence has shown that microRNAs (miRNAs) are involved in molecular pathways responsible for aging and prevalent aging-related chronic diseases. However, the lack of research linking circulating levels of miRNAs to changes in the aging brain… read more here.
Keywords: serum expression; mir 125b; alzheimer disease; mir ... See more keywords
Alpha-cardiac Actin Serum Expression Levels Detect Acute Cellular Rejection in Heart Transplant Patients
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DOI: 10.1097/tp.0000000000004273
Abstract: Background. Given the central role of sarcomeric dysfunction in cardiomyocyte biology and sarcomere alterations described in endomyocardial biopsies of transplant patients with rejection, we hypothesized that the serum expression levels of genes encoding sarcomeric proteins… read more here.
Keywords: alpha cardiac; expression levels; cardiac actin; serum expression ... See more keywords
Lower serum expression of miR-181c-5p is associated with increased plasma levels of amyloid-beta 1–40 and cerebral vulnerability in normal aging
Sign Up to like & getrecommendations! Published in 2019 at "Translational Neurodegeneration"
DOI: 10.1186/s40035-019-0174-8
Abstract: BackgroundPrevious studies have shown that expression levels of miR-181c are downregulated by amyloid-β (Aβ) deposition and chronic cerebral hypoperfusion, both factors largely associated with the development of AD. Moreover, reduced 2-[18F]fluoro-2-deoxy-D-glucose (FDG)-PET brain metabolism and… read more here.
Keywords: serum expression; 181c associated; mir 181c; expression ... See more keywords