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Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5027
Abstract: Klotho has both anticancer and hormone‐like functions. But the research on Klotho and cancer is mainly based on animal experiments and small‐scale clinical research, thus we explored the association between serum Klotho and cancer and…
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Keywords:
cancer mortality;
serum klotho;
klotho;
association serum ... See more keywords
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Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82258-5
Abstract: Klotho, an important anti-aging protein, may be related to elevated blood pressure (BP) and arterial stiffness. We aimed to investigate associations between the serum klotho concentration and peripheral/central BP and arterial stiffness based on the…
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Keywords:
serum klotho;
klotho concentration;
chinese population;
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Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz748.0310
Abstract: Klotho, which was originally identified as an aging suppressor, is a key regulator of bone and mineral metabolism. Transmembrane and soluble forms of Klotho protein have been identified. The transmembrane form serves as an obligate…
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Keywords:
coronary artery;
serum klotho;
calcium index;
calcium ... See more keywords
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Published in 2023 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac146
Abstract: BACKGROUND Endothelial dysfunction (ED) has a well-known role in promoting vascular inflammation in Behçet disease (BD). α-klotho is involved in regulation of endothelial function, and its reduction has been reported to be associated with ED.…
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Keywords:
beh disease;
serum klotho;
klotho;
klotho levels ... See more keywords
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Published in 2022 at "The Scientific World Journal"
DOI: 10.1155/2022/7274858
Abstract: Objectives Previous studies have reported conflicting results regarding the relationship between obesity and the antiaging humoral factor klotho. Thus, the present study aimed to examine the association of anthropometric measurements, weight history change, and vitamin…
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Keywords:
obesity;
serum klotho;
klotho levels;
obesity antiaging ... See more keywords
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Published in 2023 at "American journal of nephrology"
DOI: 10.1159/000531045
Abstract: INTRODUCTION Kidney stones (KSs) are associated with hematuria and renal failure and pose a significant clinical and public health concern. Diabetes is associated with a higher risk of KSs. In addition, α-Klotho (Klotho), as a…
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Keywords:
kidney stones;
health;
serum klotho;
klotho ... See more keywords
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Published in 2019 at "BMC Nephrology"
DOI: 10.1186/s12882-019-1232-2
Abstract: BackgroundHemodialysis patients suffer from a serious threat of cerebrovascular disease. Klotho, as an aging-suppressor gene, contributes to protect on vascular calcification and oxidative stress, which are the risk factors of cerebrovascular disease. The purpose of…
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Keywords:
disease hemodialysis;
cerebrovascular disease;
disease;
serum klotho ... See more keywords
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Published in 2022 at "Current aging science"
DOI: 10.2174/1874609815666220304200939
Abstract: BACKGROUND The protein klotho protects cellular function during various physiological stressors, such as exercise, however it is unknown how the age-related decline in klotho production affects responses during exercise, especially in the heat. OBJECTIVE Our…
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Keywords:
serum klotho;
exercise;
older men;
exercise temperate ... See more keywords
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Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1013747
Abstract: Background and aims Evidence indicates that serum Klotho concentration is associated with mortality in patients with chronic kidney disease (CKD). However, evidence on this association among people with hypertension is scarce. Therefore, we aimed to…
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Keywords:
klotho concentration;
mortality;
serum klotho;
cause ... See more keywords
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Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.970575
Abstract: Background Low klotho is associated with aging-related traits. However, no study has assessed the association between klotho and oral health in a large sample of population. This study aimed to explore the association between serum…
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Keywords:
health;
serum klotho;
oral health;
klotho associated ... See more keywords