Association of serum Klotho levels with cancer and cancer mortality: Evidence from National Health and Nutrition Examination Survey
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5027
Abstract: Klotho has both anticancer and hormone‐like functions. But the research on Klotho and cancer is mainly based on animal experiments and small‐scale clinical research, thus we explored the association between serum Klotho and cancer and… read more here.
Keywords: cancer mortality; serum klotho; klotho; association serum ... See more keywords
No significant association of serum klotho concentration with blood pressure and pulse wave velocity in a Chinese population
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82258-5
Abstract: Klotho, an important anti-aging protein, may be related to elevated blood pressure (BP) and arterial stiffness. We aimed to investigate associations between the serum klotho concentration and peripheral/central BP and arterial stiffness based on the… read more here.
Keywords: serum klotho; klotho concentration; chinese population;
Clinical value of serum Klotho protein in patients with acute traumatic brain injury complicated by acute kidney injury
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-05201-y
Abstract: Traumatic Brain Injury (TBI) is a major cause of mortality and morbidity, with acute kidney injury (AKI) as a common complication. This study aimed to investigate the potential of serum Klotho protein levels as a… read more here.
Keywords: serum klotho; klotho protein; injury; traumatic brain ... See more keywords
P1549Serum soluble Klotho is associated with extent of coronary artery calcification in patients with stable angina pectoris undergoing percutaneous coronary intervention
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz748.0310
Abstract: Klotho, which was originally identified as an aging suppressor, is a key regulator of bone and mineral metabolism. Transmembrane and soluble forms of Klotho protein have been identified. The transmembrane form serves as an obligate… read more here.
Keywords: coronary artery; serum klotho; calcium index; calcium ... See more keywords
Association between Serum α-Klotho Levels and Behçet Disease.
Sign Up to like & getrecommendations! Published in 2023 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac146
Abstract: BACKGROUND Endothelial dysfunction (ED) has a well-known role in promoting vascular inflammation in Behçet disease (BD). α-klotho is involved in regulation of endothelial function, and its reduction has been reported to be associated with ED.… read more here.
Keywords: beh disease; serum klotho; klotho; klotho levels ... See more keywords
Potential of Klotho as a Biomarker for Overwork
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Occupational and Environmental Medicine"
DOI: 10.1097/jom.0000000000003263
Abstract: Elevated serum soluble alpha Klotho (s-αKlotho) levels are early biomarkers for overwork-related health risks, allowing timely intervention. This finding supports healthcare policies to limit work hours and promote a healthy work-life balance, reducing overwork-related diseases.… read more here.
Keywords: klotho; klotho levels; biomarker overwork; serum klotho ... See more keywords
Circulating Klotho and mortality patterns among US cancer survivors: A cohort study
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000043471
Abstract: Klotho, a longevity hormone, exerts diverse anticancer activities. However, evidence regarding the association between serum Klotho and mortalities among cancer survivors is lacking. We examined the association between serum Klotho and the risks of all-cause… read more here.
Keywords: cancer; among cancer; mortality; serum klotho ... See more keywords
The Association of Obesity and the Antiaging Humoral Factor Klotho in Middle-Aged and Older Adults
Sign Up to like & getrecommendations! Published in 2022 at "The Scientific World Journal"
DOI: 10.1155/2022/7274858
Abstract: Objectives Previous studies have reported conflicting results regarding the relationship between obesity and the antiaging humoral factor klotho. Thus, the present study aimed to examine the association of anthropometric measurements, weight history change, and vitamin… read more here.
Keywords: obesity; serum klotho; klotho levels; obesity antiaging ... See more keywords
Association between serum Klotho and kidney stones in US middle-aged and older individuals with diabetes mellitus: Results from 2007-2016 National Health and Nutrition Survey.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of nephrology"
DOI: 10.1159/000531045
Abstract: INTRODUCTION Kidney stones (KSs) are associated with hematuria and renal failure and pose a significant clinical and public health concern. Diabetes is associated with a higher risk of KSs. In addition, α-Klotho (Klotho), as a… read more here.
Keywords: kidney stones; health; serum klotho; klotho ... See more keywords
Inverse association between serum klotho levels and C-reactive protein levels in the US population: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2024 at "BMC Cardiovascular Disorders"
DOI: 10.1186/s12872-024-04375-z
Abstract: The inverse relationship between serum Klotho levels and systemic inflammation, particularly C-reactive protein (CRP), has been suggested in limited studies. However, the association within a large and diverse population remains underexplored. We conducted a cross-sectional… read more here.
Keywords: klotho; association serum; klotho levels; serum klotho ... See more keywords
Serum klotho: a potential predictor of cerebrovascular disease in hemodialysis patients
Sign Up to like & getrecommendations! Published in 2019 at "BMC Nephrology"
DOI: 10.1186/s12882-019-1232-2
Abstract: BackgroundHemodialysis patients suffer from a serious threat of cerebrovascular disease. Klotho, as an aging-suppressor gene, contributes to protect on vascular calcification and oxidative stress, which are the risk factors of cerebrovascular disease. The purpose of… read more here.
Keywords: disease hemodialysis; cerebrovascular disease; disease; serum klotho ... See more keywords