Elevation of the serum liver enzyme levels during tolvaptan treatment in patients with autosomal dominant polycystic kidney disease (ADPKD)
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-1545-7
Abstract: BackgroundIn 2014, tolvaptan, a vasopressin receptor antagonist, was approved for the treatment of autosomal dominant polycystic kidney disease (ADPKD) in Japan. Clinical trials of tolvaptan revealed frequent occurrence of the liver function abnormality. According to… read more here.
Keywords: liver enzyme; enzyme levels; serum liver;
Population Pharmacokinetic-Pharmacodynamic Target Attainment Analysis of Flomoxef in the Serum and Liver Tissue of Patients Undergoing Hepatic Resection
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02303-21
Abstract: The purpose of this study was to investigate the population pharmacokinetics of prophylactic flomoxef based on serum and liver tissue concentrations and to demonstrate a pharmacodynamic target concentration in the serum and liver tissue exceeding… read more here.
Keywords: population; liver tissue; serum liver; tissue ... See more keywords
Serum liver enzymes and metabolic syndrome from the Rafsanjan Cohort Study
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DOI: 10.1177/10815589221141830
Abstract: Our investigation aimed at evaluating the relationship between metabolic syndrome, alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma glutamyl transferase (GGT), and alkaline phosphatase (ALP) in the Rafsanjan cohort study (RCS). We used data obtained from… read more here.
Keywords: metabolic syndrome; liver enzymes; cohort study; rafsanjan cohort ... See more keywords
Comparative Metabolomics Analysis of Juvenile Takifugu obscurus serum and Liver Samples after Exposure to Tributyltin Chloride
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DOI: 10.15244/pjoes/130680
Abstract: Tributyltin chloride (TBT-Cl), one of the most representative chemical compounds of tributyltin (TBT), is a threat to aquatic organisms due to evidence of fatal toxicity, which has attracted much interest in the scientific community. We… read more here.
Keywords: juvenile takifugu; obscurus; serum liver; takifugu obscurus ... See more keywords
Enzymatic hydrolysis of fumonisins in the gastrointestinal tract of broiler chickens
Sign Up to like & getrecommendations! Published in 2017 at "Poultry Science"
DOI: 10.3382/ps/pex280
Abstract: &NA; Fumonisins (FB) are among the most frequently detected mycotoxins in feedstuffs and finished feed, and recent data suggest that the functions of the gastrointestinal tract (GIT) in poultry species might be compromised at doses… read more here.
Keywords: gastrointestinal tract; broiler; group; serum liver ... See more keywords
Liver Involvement in Acute Respiratory Infections in Children and Adolescents – Results of a Non-interventional Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.840008
Abstract: Background In children and adults with acute respiratory tract infections (ARTI), elevations of serum liver enzyme activities are frequently observed in clinical practice. However, epidemiological data particularly in the pediatric population are very limited. The… read more here.
Keywords: non interventional; acute respiratory; study; children adolescents ... See more keywords
Short-Term Stability of Serum and Liver Extracts for Untargeted Metabolomics and Lipidomics
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DOI: 10.3390/antiox12050986
Abstract: Thermal reactions can significantly alter the metabolomic and lipidomic content of biofluids and tissues during storage. In this study, we investigated the stability of polar metabolites and complex lipids in dry human serum and mouse… read more here.
Keywords: liver; liver extracts; polar metabolites; stability ... See more keywords