Leucine-rich α2-glycoprotein as the acute-phase reactant to detect systemic juvenile idiopathic arthritis disease activity during anti-interleukin-6 blockade therapy: A case series
Sign Up to like & getrecommendations! Published in 2017 at "Modern Rheumatology"
DOI: 10.1080/14397595.2016.1270795
Abstract: Abstract Objectives: To assess the role of leucine-rich α2-glycoprotein (LRG) as a biomarker for monitoring systemic juvenile idiopathic arthritis (s-JIA) disease activity during interleukin (IL)-6 blockade treatment. Methods: We serially measured serum LRG levels in… read more here.
Keywords: lrg levels; serum lrg; blockade; disease ... See more keywords
MO945SERUM AND URINE LEUCINE RICH ALPHA-2-GLYCOPROTEIN-1 IS ASSOCIATED WITH KIDNEY TRANSPLANT INJURY AND FAILURE
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DOI: 10.1093/ndt/gfab110.0024
Abstract: Kidney transplantation is the treatment of choice for most of the patients with end stage chronic kidney disease. To improve patient and graft survival, early diagnostics and discovery of specific biomarkers is important. Leucine rich… read more here.
Keywords: serum; kidney transplant; serum lrg; post transplant ... See more keywords
AB0956 Leucine-rich alpha-2 glycoproteinis a predictable biomarker for therapeutic response and clinical relapse to biologics, but not to apremilast in patients with psoriasis
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DOI: 10.1136/annrheumdis-2018-eular.1660
Abstract: Background Leucine-rich alpha-2 glycoprotein (LRG) is a 50 kDa protein produced by hepatocytes, endothelial cells, neutrophils and macrophages, and it was identified as an inflammatory biomarker that correlates with the disease activity of autoimmune diseases such… read more here.
Keywords: biologics apremilast; leucine rich; serum lrg; biomarker ... See more keywords
Serum leucine-rich α2 glycoprotein as a potential biomarker for systemic inflammation in Parkinson’s disease
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DOI: 10.1371/journal.pone.0282153
Abstract: There is ample epidemiological and animal-model evidence suggesting that intestinal inflammation is associated with the development of Parkinson’s disease (PD). Leucine-rich α2 glycoprotein (LRG) is a serum inflammatory biomarker used to monitor the activity of… read more here.
Keywords: lrg levels; serum; serum lrg; biomarker systemic ... See more keywords