Predictive diagnosis of chronic obstructive pulmonary disease using serum metabolic biomarkers and least‐squares support vector machine
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.23641
Abstract: Development of biofluid‐based biomarkers is attractive for the diagnosis of chronic obstructive pulmonary disease (COPD) but still lacking. Thus, here we aimed to identify serum metabolic biomarkers for the diagnosis of COPD. read more here.
Keywords: chronic obstructive; diagnosis chronic; obstructive pulmonary; metabolic biomarkers ... See more keywords
Diagnosis of Unruptured Intracranial Aneurysm by High‐Performance Serum Metabolic Fingerprints
Sign Up to like & getrecommendations! Published in 2023 at "Small Methods"
DOI: 10.1002/smtd.202201486
Abstract: Unruptured intracranial aneurysm (UIA) is a high‐risk cerebrovascular saccular dilatation, the effective medical management of which depends on high‐performance diagnosis. However, most UIAs are diagnosed incidentally during neurovascular imaging modalities, which are time‐consuming and harmful… read more here.
Keywords: serum metabolic; metabolic fingerprints; diagnosis; high performance ... See more keywords
Prenatal dexamethasone exposure-induced a gender-difference and sustainable multi-organ damage in offspring rats via serum metabolic profile analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.09.007
Abstract: Prenatal dexamethasone exposure (PDE) induces developmental toxicities of multiple organs in offspring, but its serum metabolic profile changes before and after birth are unclear. Here, we employed a LC-MS-based metabolomic approach to detect serum metabolites… read more here.
Keywords: serum; offspring rats; metabolic profile; multi organ ... See more keywords
Serum Metabolic Fingerprints on Bowl-Shaped Submicroreactor Chip for Chemotherapy Monitoring
Sign Up to like & getrecommendations! Published in 2022 at "ACS Nano"
DOI: 10.1021/acsnano.1c09864
Abstract: Chemotherapy is a primary cancer treatment strategy, the monitoring of which is critical to enhancing the survival rate and quality of life of cancer patients. However, current chemotherapy monitoring mainly relies on imaging tools with… read more here.
Keywords: serum metabolic; chemotherapy monitoring; bowl; bowl shaped ... See more keywords
Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2122245119
Abstract: Significance Breast cancer (BrCa) is the most common cancer worldwide, and high-performance metabolic analysis is emerging in diagnosis and prognosis of BrCa. Here, we used nanoparticle-enhanced laser desorption/ionization mass spectrometry to record serum metabolic fingerprints… read more here.
Keywords: serum metabolic; serum; diagnosis prognosis; breast cancer ... See more keywords
Effects of acupuncture on anthropometric and serum metabolic parameters in premenopausal overweight and obese women: a randomized, patient- and assessor-blind, sham-controlled clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "Acupuncture in Medicine"
DOI: 10.1177/0964528420912259
Abstract: Objective: The aim of this study was to examine the effect of acupuncture on obesity-related parameters with regard to metabolomics. Methods: This two-arm parallel, patient- and assessor-blind, sham-controlled randomized clinical trial included 120 obese participants.… read more here.
Keywords: patient assessor; trial; acupuncture; group ... See more keywords
Lipidomics coupled with pathway analysis characterizes serum metabolic changes in response to potassium oxonate induced hyperuricemic rats
Sign Up to like & getrecommendations! Published in 2019 at "Lipids in Health and Disease"
DOI: 10.1186/s12944-019-1054-z
Abstract: BackgroundHyperuricemia as a metabolic disease is usually associated with lipid metabolic disorder. The purpose of this study is to identify potential lipid biomarkers and provide the evidence for the relationship between hyperuricemia and lipid-related diseases.MethodsLipidomics-a… read more here.
Keywords: metabolic changes; metabolism; analysis; hyperuricemia ... See more keywords
Serum metabolic profiling of rats infected with Clonorchis sinensis using LC-MS/MS method
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.1040330
Abstract: Background Clonorchiasis is an important foodborne parasitic disease. The omics-based-techniques could illuminate parasite biology and further make innovations in the research for parasitic diseases. However, knowledge about the serum metabolic profiles and related metabolic pathways… read more here.
Keywords: serum metabolic; metabolism; sinensis; clonorchiasis ... See more keywords
Intestinal Microbiota and Serum Metabolic Profile Responded to Two Nutritional Different Diets in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2021.813757
Abstract: There is an interaction and bidirectional selection between dietary intake and gut microbiota due to the different efficiency of nutrients in the gut. The nutritional composition of germ-free (GF) diets differs significantly from specific pathogen-free… read more here.
Keywords: serum metabolic; microbiota; spf mice; metabolic profile ... See more keywords
Polycythemia Vera and Essential Thrombocythemia Patients Exhibit Unique Serum Metabolic Profiles Compared to Healthy Individuals and Secondary Thrombocytosis Patients
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13030482
Abstract: Simple Summary Current diagnosis of myeloproliferative neoplasms (MPNs), including polycythemia vera (PV) and essential thrombocythemia (ET), is controversial due to limitations associated with the lack of reproducibility, subjectivity and the presence of common somatic mutations… read more here.
Keywords: thrombocytosis patients; polycythemia vera; vera essential; secondary thrombocytosis ... See more keywords
Diagnostic biomarker panels of osteoarthritis: UPLC-QToF/MS-based serum metabolic profiling
Sign Up to like & getrecommendations! Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.14563
Abstract: Osteoarthritis (OA) is the most common joint disease in the world, characterized by pain and loss of joint function, which has led to a serious reduction in the quality of patients’ lives. In this work,… read more here.
Keywords: serum metabolic; biomarker panels; panels osteoarthritis; osteoarthritis uplc ... See more keywords