Biomarkers for pancreatic cancer based on tissue and serum metabolomics analysis in a multicenter study
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5296
Abstract: Early detection of pancreatic ductal adenocarcinoma (PDAC) may improve the prognosis of patients. This study was to identify metabolic features of PDAC and to discover early detection biomarkers for PDAC by tissue and serum metabolomics… read more here.
Keywords: serum metabolomics; tissue serum; metabolomics analysis;
Prediction of sublingual immunotherapy efficacy in allergic rhinitis by serum metabolomics analysis.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.107211
Abstract: BACKGROUND Allergen-specific immunotherapy (ASIT) is currently the only therapy for allergic rhinitis (AR) that can induce immune tolerance to allergens. However, the course of ASIT is long and there is no objective biomarker to predict… read more here.
Keywords: allergic rhinitis; analysis; group; serum ... See more keywords
Serum metabolomics approach to monitor the changes in metabolite profiles following renal transplantation
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74245-z
Abstract: Systemic metabolic changes after renal transplantation reflect the key processes that are related to graft accommodation. In order to describe and better understand these changes, the 1HNMR based metabolomics approach was used. The changes of… read more here.
Keywords: changes renal; renal transplantation; approach monitor; transplantation ... See more keywords
Serum metabolomics indicates ferroptosis in patients with pantothenate kinase associated neurodegeneration
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-94838-w
Abstract: The core syndrome among NBIA disorders is pantothenate kinase-associated neurodegeneration (PKAN), an autosomal recessive disorder caused by mutations in the PANK2 gene. There is no therapy for PKAN; only symptomatic treatment is available. Our work… read more here.
Keywords: serum metabolomics; ferroptosis; pantothenate kinase; kinase associated ... See more keywords
Untargeted serum metabolomics and tryptophan metabolism profiling in type 2 diabetic patients with diabetic glomerulopathy
Sign Up to like & getrecommendations! Published in 2021 at "Renal Failure"
DOI: 10.1080/0886022x.2021.1937219
Abstract: Abstract Diabetic glomerulopathy (DG) remains the prevalent microvascular complication and leading cause of shortened lifespan in type-2 diabetes mellitus (T2DM) despite improvement in hyperglycemia control. Considering the pivotal role of kidney in metabolism, using untargeted… read more here.
Keywords: diabetic glomerulopathy; metabolomics tryptophan; metabolism; untargeted serum ... See more keywords
Integration of serum metabolomics and network pharmacology reveals the immunoenhancing mechanisms of Qishenbuqi capsules.
Sign Up to like & getrecommendations! Published in 2023 at "Toxicology research"
DOI: 10.1093/toxres/tfad008
Abstract: Introduction Qishenbuqi capsule (QSBQC), a listed Chinese patent prescription, comprises of 4 herbs. Clinically, it has been shown to improve immune functions. Methods Subjects with Qi deficiency and non-Qi deficiency were recruited, who then took… read more here.
Keywords: cells cd3; pharmacology; deficiency; serum metabolomics ... See more keywords
Salivary microbiome and serum metabolomics add to clinical biomarkers to predict 6-month hospitalizations in a multi-center cirrhosis outpatient cohort.
Sign Up to like & getrecommendations! Published in 2025 at "Hepatology"
DOI: 10.1097/hep.0000000000001462
Abstract: BACKGROUND AIMS Prognosticating outcomes such as hospitalizations in cirrhosis outpatients is challenging, especially with changing etiologies and demographics. Aim: Determine impact of multi-omic strategies on outcome prediction. APPROACH RESULTS NACSELD3 enrolls cirrhosis outpatients with controlled/eradicated… read more here.
Keywords: serum; cirrhosis; salivary microbiome; serum metabolomics ... See more keywords
Changes of serum metabolomics and gut microbiota reveal specific characteristics of Children with Febrile Seizures.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of neurology"
DOI: 10.1111/ene.15275
Abstract: BACKGROUND Febrile seizures (FS) pose a severe threat to the neurological development of children. Probing the abnormality of host metabolism is essential for the prevention, diagnosis and treatment of FS. METHODS Based on the clinically… read more here.
Keywords: specific characteristics; characteristics children; gut microbiota; changes serum ... See more keywords
The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.70662
Abstract: The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs… read more here.
Keywords: traditional chinese; treatments disease; different treatments; serum metabolomics ... See more keywords
Serum metabolomics in pulmonary sarcoidosis: metabolic signatures across prognoses
Sign Up to like & getrecommendations! Published in 2025 at "BMC Pulmonary Medicine"
DOI: 10.1186/s12890-025-03863-y
Abstract: Sarcoidosis is a systemic inflammatory disease, primarily affecting the lungs, with a prognosis that varies widely among patients. While some patients recover spontaneously after diagnosis, others experience disease progression. Currently, the metabolomic profile associated with… read more here.
Keywords: pulmonary sarcoidosis; metabolomics pulmonary; serum metabolomics; metabolic signatures ... See more keywords
Serum metabolomics reveals systemic metabolic alterations of Graves’ disease before and after antithyroid drug treatment
Sign Up to like & getrecommendations! Published in 2025 at "Endocrine Connections"
DOI: 10.1530/ec-25-0078
Abstract: Objective This study aimed to utilize untargeted metabolomics to analyze changes of serum metabolites before and after methimazole treatment in patients with Graves’ disease (GD). Methods Total 40 GD patients and 30 healthy volunteers were… read more here.
Keywords: reveals systemic; treatment; graves disease; systemic metabolic ... See more keywords