Serum PCSK9 levels at the second nivolumab cycle predict overall survival in elderly patients with NSCLC: a pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-019-02367-z
Abstract: Monoclonal antibodies targeting PD-1 are used for treating NSCLC. To date, proprotein convertase subtilisin/kexin type 9 (PCSK9) has been poorly investigated in the oncologic field. Here, we aimed at evaluating whether serum PCSK9 might represent… read more here.
Keywords: pilot study; study; cycle; pcsk9 levels ... See more keywords
Increased serum PCSK9 levels are associated with renal function impairment in patients with type 2 diabetes mellitus
Sign Up to like & getrecommendations! Published in 2023 at "Renal Failure"
DOI: 10.1080/0886022x.2023.2215880
Abstract: Abstract Purpose The purpose of this study was to investigate the association between serum proprotein convertase subtilisin/kexin type 9 (PCSK9) levels and renal function impairment in type 2 diabetes mellitus (T2DM) patients. Methods PCSK9 levels… read more here.
Keywords: serum pcsk9; pcsk9; pcsk9 tertile; renal function ... See more keywords
Serum PCSK9 levels, but not PCSK9 polymorphisms, are associated with CAD risk and lipid profiles in southern Chinese Han population
Sign Up to like & getrecommendations! Published in 2018 at "Lipids in Health and Disease"
DOI: 10.1186/s12944-018-0859-5
Abstract: BackgroundGenetic and environment factors affect the occurrence and development of coronary artery disease (CAD). Proprotein convertase subtilisin/kexin type 9 (PCSK9), has been investigated extensively in the field of lipid metabolism and CAD. We performed this… read more here.
Keywords: cad; pcsk9 levels; pcsk9; population ... See more keywords
Interplay between microRNAs, Serum Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), and Lipid Parameters in Patients with Very High Lipoprotein(a) Treated with PCSK9 Inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14030632
Abstract: Proprotein convertase subtilisin/kexin type 9 (PCSK9) has an important function in the regulation of lipid metabolism. PCSK9 reduces hepatic low-density lipoprotein receptors, thereby increasing low-density lipoprotein cholesterol levels. However, its regulation remains to be elucidated,… read more here.
Keywords: serum pcsk9; pcsk9 inhibitors; pcsk9; expression ... See more keywords