Serum protein signatures differentiate paediatric autoimmune/inflammatory disorders.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108790
Abstract: Because of their rarity, limited awareness among non-specialists, and significant overlaps in their clinical presentation, childhood autoimmune/inflammatory conditions represent a diagnostic and therapeutic challenge. Juvenile idiopathic arthritis (JIA), with its 7 sub-forms, is the most… read more here.
Keywords: disease; serum protein; differentiate paediatric; protein signatures ... See more keywords
Serum protein expression profiling and bioinformatics analysis in workers occupationally exposed to chromium (VI).
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.05.026
Abstract: Cr(VI) is widely-recognized as occupational and environmental contaminant, but the precise underlying mechanisms of Cr(VI) induced carcinogenic toxicity remain to be elucidated. Among kinds of toxic mechanisms, alteration of protein profiling usually elaborate a key… read more here.
Keywords: protein; serum proteins; biomarkers exposure; serum ... See more keywords
NOVEL SERUM PROTEIN BIOMARKERS SIGNIFICANTLY UP-REGULATED IN LGE NEGATIVE DMD SUBJECTS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)31688-0
Abstract: Cardiac disease in Duchenne muscular dystrophy (DMD) is now the leading cause of death. Increasing cardiac fibrosis demonstrated by late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) is associated with worse outcomes in… read more here.
Keywords: dmd; novel serum; serum protein; significantly regulated ... See more keywords
Blood-based protein profiling identifies serum protein c-KIT as a novel biomarker for hypertrophic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80868-z
Abstract: Hypertrophic cardiomyopathy (HCM) is one of the most common hereditary heart diseases and can be classified into an obstructive (HOCM) and non-obstructive (HNCM) form. Major characteristics for HCM are the hypertrophy of cardiomyocytes and development… read more here.
Keywords: healthy controls; hypertrophic cardiomyopathy; serum protein; patients hcm ... See more keywords
Serum protein changes in a rat model of chronic pain show a correlation between animal and humans
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41723
Abstract: In previous works we showed the overexpression of some proteins in biological fluids from patients suffering chronic pain. In this proteomic study we analysed serum from a rat model of neuropathic pain obtained by the… read more here.
Keywords: serum protein; rat model; cci rats; chronic pain ... See more keywords
Serum protein corona-responsive autophagy tuning in cells.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr05770b
Abstract: Autophagy represents an important cellular response to nanoparticles (NPs), whose modulation holds great promise for developing nanomedicine. Here, we systematically studied cell autophagy responses elicited by the NP-protein corona with diverse protein corona types surrounding… read more here.
Keywords: serum protein; corona responsive; protein corona; cell autophagy ... See more keywords
Surface-regulated injection dose response of ultrasmall luminescent gold nanoparticles.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr01784a
Abstract: With the rapid growth of the use of renal-clearable nanomedicines in disease targeting and therapy, a fundamental understanding of their injection dose responses is of great importance for future translation to clinical settings. Using glutathione-coated… read more here.
Keywords: injection; gold nanoparticles; injection dose; serum protein ... See more keywords
Serum protein electrophoretic pattern in dairy cows during the periparturient period
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Animal Research"
DOI: 10.1080/09712119.2016.1256293
Abstract: ABSTRACT This study was aimed at the evaluation of changes in the concentrations of serum protein fractions in 10 clinically healthy dairy cows in the period from 1 week before to 6 weeks after calving.… read more here.
Keywords: protein electrophoretic; dairy cows; period; serum protein ... See more keywords
Achieving Expert-Level Interpretation of Serum Protein Electrophoresis through Deep Learning Driven by Human Reasoning.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical chemistry"
DOI: 10.1093/clinchem/hvab133
Abstract: BACKGROUND Serum protein electrophoresis (SPE) is a common clinical laboratory test, mainly indicated for the diagnosis and follow-up of monoclonal gammopathies. A time-consuming and potentially subjective human expertise is required for SPE analysis to detect… read more here.
Keywords: serum protein; interpretation; protein electrophoresis;
Serum protein electrophoresis reference intervals for six species of wild-sampled sharks in South Florida.
Sign Up to like & getrecommendations! Published in 2022 at "Integrative and comparative biology"
DOI: 10.1093/icb/icac063
Abstract: Serum proteins found in the blood have been used as diagnostic markers in both human and animal medicine. Evaluating proteins in the blood of sharks may be a valuable way to assess shark health. The… read more here.
Keywords: serum; serum protein; protein electrophoresis; reference intervals ... See more keywords
The complexity of minocycline serum protein binding
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkx039
Abstract: Objectives Serum protein binding is critical for understanding the pharmacology of antimicrobial agents. Tigecycline and eravacycline were previously reported to have atypical non-linear protein binding; the percentage of free fraction decreased with increasing total concentration.… read more here.
Keywords: serum protein; minocycline; concentration; protein binding ... See more keywords