SO013CRUCIAL ROLE OF SERUM RESPONSE FACTOR IN EPITHELIAL-MESENCHYMAL TRANSITION OF RENAL TUBULAR EPITHELIAL CELLS IN HYPERUREICEMIC NEPHROPATHY
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa139.so013
Abstract: To investigate the role of serum response factor (SRF) in epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells (TECs) in hyperuricemic nephropathy (HN). The expression of SRF, epithelial markers (E-cadherin and ZO-1) and mesenchymal markers… read more here.
Keywords: epithelial cells; role serum; srf; renal tubular ... See more keywords
Serum response factor regulates smooth muscle contractility via myotonic dystrophy protein kinases and L-type calcium channels
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171262
Abstract: Serum response factor (SRF) transcriptionally regulates expression of contractile genes in smooth muscle cells (SMC). Lack or decrease of SRF is directly linked to a phenotypic change of SMC, leading to hypomotility of smooth muscle… read more here.
Keywords: muscle; srf; smooth muscle; serum response ... See more keywords
Serum response factor promotes axon regeneration following spinal cord transection injury
Sign Up to like & getrecommendations! Published in 2023 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.367974
Abstract: Studies have shown that serum response factor is beneficial for axonal regeneration of peripheral nerves. However, its role after central nervous system injury remains unclear. In this study, we established a rat model of T9–T10… read more here.
Keywords: serum response; response factor; spinal cord;
Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.75106
Abstract: Serum response factor (SRF) is an essential transcription factor that influences many cellular processes including cell proliferation, migration, and differentiation. SRF directly regulates and is required for immediate early gene (IEG) and actin cytoskeleton-related gene… read more here.
Keywords: neural crest; factor; response factor; cardiac neural ... See more keywords