Serum Sclerostin and Bone Morphogenetic Protein-2 Levels in Patients with Ankylosing Spondylitis: A Meta-Analysis
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DOI: 10.1007/s00223-019-00542-z
Abstract: Various studies have investigated the serum sclerostin and bone morphogenetic protein-2 (BMP-2) levels in patients with ankylosing spondylitis (AS), but the results were inconsistent. The aim of this meta-analysis was to synthetically assess the associations… read more here.
Keywords: levels patients; ankylosing spondylitis; sclerostin; analysis ... See more keywords
Associations of serum sclerostin with bone mineral density, markers of bone metabolism and thalassaemia characteristics in adult patients with transfusion-dependent beta-thalassaemia
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DOI: 10.1080/07853890.2020.1744708
Abstract: Abstract Aim of the study: To assess serum sclerostin in transfusion-dependent beta-thalassaemia patients versus healthy controls and to examine its associations with bone mineral density, bone metabolism markers and beta thalassaemia alterations. Material and methods:… read more here.
Keywords: thalassaemia; beta thalassaemia; dependent beta; serum sclerostin ... See more keywords
Serum sclerostin in vascular calcification in CKD: a meta-analysis
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DOI: 10.1080/0886022x.2023.2186151
Abstract: Abstract Vascular calcification (VC) is recognized as a predictor of all-cause and CVD mortality in chronic kidney disease (CKD). VC in CKD is possibly associated with serum sclerostin. The study systematically investigated the role of… read more here.
Keywords: ckd; serum sclerostin; meta analysis;
Serum Sclerostin and Its Association with Bone Turnover Marker in Metabolic Bone Diseases
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DOI: 10.1155/2022/7902046
Abstract: Sclerostin is a secreted inhibitor of Wnt/β-catenin signaling that is mainly produced by osteocytes and is an important regulator of bone remodeling. Some studies have evaluated serum sclerostin levels in metabolic bone diseases, but the… read more here.
Keywords: serum sclerostin; bone; sclerostin; bone turnover ... See more keywords
Serum Sclerostin Levels and Mortality in Hemodialysis Patients: An 8-Year Prospective Study
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DOI: 10.1159/000528795
Abstract: Introduction: Sclerostin is an osteocyte-derived inhibitor of bone formation and is increased in kidney failure. Sclerostin might be involved in the pathogenesis of vascular calcification, but few studies have examined the association between sclerostin and… read more here.
Keywords: serum sclerostin; sclerostin; mortality; sclerostin levels ... See more keywords
SUN-537 Progesterone Therapy and Serum Sclerostin Levels in Healthy Menopausal Women: A 3-month Randomized, Placebo Controlled Clinical Trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Endocrine Society"
DOI: 10.1210/js.2019-sun-537
Abstract: Abstract Sclerostin is an osteocyte-produced glycoprotein that inhibits the WNT/β-catenin pathway essential for bone formation. Sclerostin was postulated to relate to normal bone metabolism in 2001; we still have an incomplete understanding of its regulation.… read more here.
Keywords: serum sclerostin; sclerostin; month; progesterone ... See more keywords
Relationships between Circulating Sclerostin, Bone Marrow Adiposity, Other Adipose Deposits and Lean Mass in Post-Menopausal Women
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DOI: 10.3390/ijms24065922
Abstract: Sclerostin is a Wnt signaling pathway inhibitor that negatively regulates bone formation. Bone-marrow-derived stromal cell (BMSC) differentiation is influenced by the Wnt pathway, leading to the hypothesis that higher levels of sclerostin might be associated… read more here.
Keywords: circulating sclerostin; serum sclerostin; bone marrow; sclerostin ... See more keywords
Decreased Serum Level of Sclerostin in Older Adults with Sarcopenia
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DOI: 10.3803/enm.2022.1428
Abstract: Background Although muscles and bones interact with each other through various secretory factors, the role of sclerostin, an osteocyte-secreted factor, on muscle metabolism has not been well studied. We investigated the levels of serum sclerostin… read more here.
Keywords: older adults; serum sclerostin; sclerostin; muscle ... See more keywords
Does oxidative status affect serum sclerostin levels in patients with type 2 diabetes mellitus?
Sign Up to like & getrecommendations! Published in 2023 at "Folia medica"
DOI: 10.3897/folmed.65.e72953
Abstract: INTRODUCTION Sclerostin is a glycoprotein known as a negative regulator of bone formation, predominantly expressed by mature osteocytes. There is no causative evidence information on the role of sclerostin in the pathogenesis of type 2… read more here.
Keywords: oxidative status; serum sclerostin; sclerostin; type diabetes ... See more keywords