The utility of MASS‐FIX to detect and monitor monoclonal proteins in the clinic
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24772
Abstract: The detection and quantification of monoclonal‐proteins (M‐proteins) are necessary for the diagnosis and evaluation of response in plasma cell dyscrasias. Immunoglobulin enrichment‐coupled with matrix‐assisted laser desorption ionization time‐of‐flight mass‐spectrometry (MASS‐FIX) is a simple and inexpensive… read more here.
Keywords: monoclonal proteins; serum urine; mass; mass fix ... See more keywords
Extraction and detection of bisphenol A in human serum and urine by aptamer-functionalized magnetic nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0801-0
Abstract: AbstractA new type of magnetic nanoparticles (MNPs), as the absorbents of bisphenol A (BPA), was prepared by functionalization of Fe3O4@SiO2 with BPA-specific aptamer in this work. ssDNA aptamer was immobilized on the Fe3O4@SiO2 surface through… read more here.
Keywords: detection; bpa; magnetic nanoparticles; human serum ... See more keywords
GC–MS measurement of biological NG-hydroxy-l-arginine, a stepmotherly investigated endogenous nitric oxide synthase substrate and arginase inhibitor
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-02695-x
Abstract: Abstractl-Arginine is converted by nitric oxide synthase (NOS) to l-citrulline and nitric oxide (NO). NG-Hydroxy-l-arginine (NOHA) is the isolable intermediate of this reaction. NOHA has been identified in biological samples by gas chromatography–mass spectrometry (GC–MS)… read more here.
Keywords: hydroxy arginine; arginine; serum urine; oxide synthase ... See more keywords
Serum and urine analysis with gold nanoparticle-assisted laser desorption/ionization mass spectrometry for renal cell carcinoma metabolic biomarkers discovery.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in medical sciences"
DOI: 10.1016/j.advms.2021.07.003
Abstract: PURPOSE Renal cell carcinoma (RCC) is a very aggressive and often fatal heterogeneous disease that is usually asymptomatic until late in the disease. There is an urgent need for RCC specific biomarkers that may be… read more here.
Keywords: renal cell; cell carcinoma; serum urine; gold nanoparticle ... See more keywords
Metabolomic study of serum, urine and bronchoalveolar lavage fluid based on gas chromatography mass spectrometry to delve into the pathology of lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"
DOI: 10.1016/j.jpba.2018.09.055
Abstract: &NA; This study explores for the first time the combination of serum, urine and bronchoalveolar lavage fluid (BALF) to deep insight into the pathology of lung cancer (LC) using a metabolomic platform based on gas… read more here.
Keywords: urine bronchoalveolar; fluid; study; pathology ... See more keywords
Neopterin-Imprinted Columns for Selective Neopterin Recognition from Serum and Urine Samples
Sign Up to like & getrecommendations! Published in 2021 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2021.05.022
Abstract: Abstract Neopterin (Np), a catabolic product of guanosine triphosphate (GTP), is synthesized by human macrophages and is an important indicator of cellular immune system activation. Np is associated with the activated cellular immune response and… read more here.
Keywords: columns selective; serum urine; imprinted columns; neopterin imprinted ... See more keywords
Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague–Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles
Sign Up to like & getrecommendations! Published in 2019 at "Translational Oncology"
DOI: 10.1016/j.tranon.2019.04.019
Abstract: Gastrointestinal toxicity is a frequently observed adverse event during cancer treatment with traditional chemotherapeutics. Currently, traditional chemotherapeutics are often combined with targeted biologic agents. These biologics, however, possess a distinct toxicity profile, and they may… read more here.
Keywords: week; metabolic changes; treatment; aflibercept erlotinib ... See more keywords
Effects of Histidine Supplementation on Global Serum and Urine 1H NMR-based Metabolomics and Serum Amino Acid Profiles in Obese Women from a Randomized Controlled Study.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.7b00030
Abstract: The aim of current study was to investigate the metabolic changes associated with histidine supplementation in serum and urine metabolic signatures and serum amino acid (AA) profiles. Serum and urine 1H NMR-based metabolomics and serum… read more here.
Keywords: urine nmr; histidine supplementation; study; serum urine ... See more keywords
Responses in multiple myeloma should be assigned according to serum, not urine, free light chain measurements
Sign Up to like & getrecommendations! Published in 2018 at "Leukemia"
DOI: 10.1038/s41375-018-0339-y
Abstract: The most recent update to the International Myeloma Working Group consensus criteria places a strong emphasis on the need for more sensitive haematological markers of response driven by the success of novel therapies. One such… read more here.
Keywords: free light; myeloma; multiple myeloma; serum urine ... See more keywords
Serum and urine 1H NMR-based metabolomics in the diagnosis of selected thyroid diseases
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09203-3
Abstract: Early detection of nodular thyroid diseases including thyroid cancer is still primarily based on invasive procedures such as fine-needle aspiration biopsy. Therefore, there is a strong need for development of new diagnostic methods that could… read more here.
Keywords: urine nmr; thyroid diseases; serum urine; based metabolomics ... See more keywords
ASIC3-dependent metabolomics profiling of serum and urine in a mouse model of fibromyalgia
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-48315-w
Abstract: Fibromyalgia (FM) is characterized by chronic widespread pain. The pathogenesis of FM remains unclear. No specific biomarkers are available. Animal models of FM may provide an opportunity to explore potential biomarkers in a relative homogenous… read more here.
Keywords: metabolomics profiling; urine mouse; serum urine; mouse model ... See more keywords