Inhibition of melanin production by sesquiterpene lactones from Saussurea lappa and their analogues
Sign Up to like & getrecommendations! Published in 2019 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-019-02338-0
Abstract: This research is aimed towards the discovery of a novel skin whitening agent from sesquiterpene lactones. We screened nine sesquiterpene lactones from Saussurea lappa root extracts, costunolide (1), α-, β-, γ-cyclocostunolides (2, 3, 4), santamarine… read more here.
Keywords: sesquiterpene; melanin; inhibition; sesquiterpene lactones ... See more keywords
Antiamoebic effects of sesquiterpene lactones isolated from the zoanthid Palythoa aff. clavata.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104682
Abstract: Opportunistic parasitic protozoa of genus Acanthamoeba are responsible to cause severe infections in humans such as Acanthamoeba Keratitis or Amoebic Granulomatous Encephalitis. Current treatments are usually toxic and inefficient and there is a need to… read more here.
Keywords: antiamoebic effects; lactones isolated; sesquiterpene lactones; palythoa aff ... See more keywords
Elephantopinolide A-P, germacrane-type sesquiterpene lactones from Elephantopus scaber induce apoptosis, autophagy and G2/M phase arrest in hepatocellular carcinoma cells.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112362
Abstract: Chromatographic purification of Elephantopus scaber led to 16 new germacrane-type sesquiterpene lactones (1-16), named elephantopinolide A-P, along with a known analogue (17). Their structures were confirmed by comprehensive spectroscopic analyses, single-crystal X-ray diffraction, and comparison… read more here.
Keywords: elephantopus scaber; sesquiterpene lactones; germacrane type; induce apoptosis ... See more keywords
Sesquiterpene lactones in sunflower oil
Sign Up to like & getrecommendations! Published in 2021 at "Lwt - Food Science and Technology"
DOI: 10.1016/j.lwt.2021.111047
Abstract: Abstract Sunflower, Helianthus annuus, is one of the world's most important oil crops and sunflower oil is esteemed for its high content of unsaturated fatty acids together with the occurrence of relatively high amounts of… read more here.
Keywords: sesquiterpene lactones; sunflower oil; oil; lactones sunflower ... See more keywords
Studies on the sesquiterpene lactones from Laurus novocanariensis lead to the clarification of the structures of 1-epi-tatridin B and its epimer tatridin B.
Sign Up to like & getrecommendations! Published in 2018 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2018.05.014
Abstract: The germacranolide 1-epi-tatridin B has been isolated from the aerial parts of Laurus novocanariensis. We have observed that the identification of this lactone and its epimer tetradin B in the scientific literature is confusing and… read more here.
Keywords: epi tatridin; epimer; sesquiterpene lactones; laurus novocanariensis ... See more keywords
Sesquiterpene lactones from Artemisia mongolica.
Sign Up to like & getrecommendations! Published in 2022 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2022.113158
Abstract: Twelve undescribed sesquiterpene lactones and seven known sesquiterpene lactones were isolated from the whole plant of Artemisia mongolica. Their structures were elucidated based on the interpretation of NMR, HRESIMS, and electronic circular dichroism (ECD) data.… read more here.
Keywords: lactones artemisia; artemisia mongolica; sesquiterpene lactones; activity ... See more keywords
NF-κB inhibitory sesquiterpene lactones from Lebanese Laurus nobilis
Sign Up to like & getrecommendations! Published in 2019 at "Phytochemistry Letters"
DOI: 10.1016/j.phytol.2019.02.003
Abstract: Abstract The leaves of Laurus nobilis, commonly called as bay leaves, have been traditionally used for the treatment of inflammatory symptoms. As a part of the research on the characterization of bioactive constituents from natural… read more here.
Keywords: lebanese laurus; sesquiterpene lactones; lactones lebanese; inhibitory sesquiterpene ... See more keywords
Antiprotozoal Sesquiterpene Lactones and Other Constituents from Tarchonanthus camphoratus and Schkuhria pinnata.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b00747
Abstract: In continuation of a search for new antiprotozoal agents from plants of the family Asteraceae, Tarchonanthus camphoratus and Schkuhria pinnata have been investigated. By following the promising in vitro activity of the dichloromethane extracts from… read more here.
Keywords: tarchonanthus camphoratus; hydroxy; antiprotozoal sesquiterpene; schkuhria pinnata ... See more keywords
Identification and quantification of seven sesquiterpene lactones in Inula britannica by HPLC-DAD-MS
Sign Up to like & getrecommendations! Published in 2019 at "Analytical Methods"
DOI: 10.1039/c9ay00118b
Abstract: Inula britannica is a traditional Chinese medicinal herb. read more here.
Keywords: inula britannica; sesquiterpene lactones; seven sesquiterpene; quantification seven ... See more keywords
Antiproliferative and cytotoxic effects of sesquiterpene lactones isolated from Ambrosia artemisiifolia on human adenocarcinoma and normal cell lines
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Biology"
DOI: 10.1080/13880209.2022.2103574
Abstract: Abstract Context Ambrosia artemisiifolia L. (Asteraceae) contains sesquiterpene lactones as characteristic secondary metabolites. Many of these compounds exert antiproliferative and cytotoxic effects. Objective To isolate the sesquiterpene lactones from the aerial part of A. artemisiifolia… read more here.
Keywords: cell; cytotoxic effects; cell line; sesquiterpene lactones ... See more keywords
Inhibition of human cytochromes P450 2A6 and 2A13 by flavonoids, acetylenic thiophenes and sesquiterpene lactones from Pluchea indica and Vernonia cinerea
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Enzyme Inhibition and Medicinal Chemistry"
DOI: 10.1080/14756366.2017.1363741
Abstract: Abstract The human liver cytochrome P450 (CYP) 2A6 and the respiratory CYP2A13 enzymes play role in nicotine metabolism and activation of tobacco-specific nitrosamine carcinogens. Inhibition of both enzymes could offer a strategy for smoking abstinence… read more here.
Keywords: pluchea indica; inhibition; sesquiterpene lactones; acetylenic thiophenes ... See more keywords