BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency
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DOI: 10.1093/nar/gkab034
Abstract: Abstract Maintenance of stem-cell identity requires proper regulation of enhancer activity. Both transcription factors OCT4/SOX2/NANOG and histone methyltransferase complexes MLL/SET1 were shown to regulate enhancer activity, but how they are regulated in embryonic stem cells… read more here.
Keywords: enhancer promoter; set1 complexes; maintains pluripotency; mll set1 ... See more keywords